Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression
S Galland, I Stamenkovic - The Journal of pathology, 2020 - Wiley Online Library
Mesenchymal stem or stromal cells (MSCs) are pluripotent cells implicated in a broad range
of physiological events, including organogenesis and maintenance of tissue homeostasis as …
of physiological events, including organogenesis and maintenance of tissue homeostasis as …
Osteoinduction: a review of old concepts with new standards
Since the discovery of osteoinduction in the early 20th century, innovative biomaterials with
osteoinductive potential have emerged. Over the last 50 years, however, our ability to …
osteoinductive potential have emerged. Over the last 50 years, however, our ability to …
[HTML][HTML] Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human …
N Fekete, M Gadelorge, D Fürst, C Maurer… - …, 2012 - Taylor & Francis
Background aims. The clinical use of human mesenchymal stromal cells (MSC) requires ex
vivo expansion in media containing supplements such as fetal bovine serum or …
vivo expansion in media containing supplements such as fetal bovine serum or …
[HTML][HTML] Growth factor regulation of proliferation and survival of multipotential stromal cells
Multipotential stromal cells (MSCs) have been touted to provide an alternative to
conservative procedures of therapy, be it heart transplants, bone reconstruction, kidney …
conservative procedures of therapy, be it heart transplants, bone reconstruction, kidney …
The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration
Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell
types and have been widely used in tissue engineering application. In tissue engineering, a …
types and have been widely used in tissue engineering application. In tissue engineering, a …
Hydrogels for large-scale expansion of stem cells
S Yin, Y Cao - Acta biomaterialia, 2021 - Elsevier
Stem cells demonstrate considerable promise for various preclinical and clinical
applications, including drug screening, disease treatments, and regenerative medicine …
applications, including drug screening, disease treatments, and regenerative medicine …
C3a and C5a are chemotactic factors for human mesenchymal stem cells, which cause prolonged ERK1/2 phosphorylation
IU Schraufstatter, RG DiScipio, M Zhao… - The Journal of …, 2009 - journals.aai.org
Mesenchymal stem cells (MSCs) have a great potential for tissue repair, especially if they
can be delivered efficiently to sites of tissue injury. Since complement activation occurs …
can be delivered efficiently to sites of tissue injury. Since complement activation occurs …
[HTML][HTML] How to hit mesenchymal stromal cells and make the tumor microenvironment immunostimulant rather than immunosuppressive
Experimental evidence indicates that mesenchymal stromal cells (MSCs) may regulate
tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence …
tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence …
PDGF receptor β is a potent regulator of mesenchymal stromal cell function
A Tokunaga, T Oya, Y Ishii, H Motomura… - Journal of Bone and …, 2008 - academic.oup.com
Mesenchymal stromal cells (MSCs) in bone marrow are important for bone homeostasis.
Although platelet‐derived growth factor (PDGF) has been reported to be involved in …
Although platelet‐derived growth factor (PDGF) has been reported to be involved in …
Dysregulation of bone remodeling by imatinib mesylate
Imatinib mesylate is a rationally designed tyrosine kinase inhibitor that has revolutionized
the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors. Although the …
the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors. Although the …