Cell culture in microfluidic droplets

S Sart, G Ronteix, S Jain, G Amselem… - Chemical …, 2022 - ACS Publications
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

Recent methods of droplet microfluidics and their applications in spheroids and organoids

Y Wang, M Liu, Y Zhang, H Liu, L Han - Lab on a Chip, 2023 - pubs.rsc.org
Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …

Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

[HTML][HTML] Nanoparticle-induced immune response: Health risk versus treatment opportunity?

K Pondman, S Le Gac, U Kishore - Immunobiology, 2023 - Elsevier
Nanoparticles (NPs) are not only employed in many biomedical applications in an
engineered form, but also occur in our environment, in a more hazardous form. NPs interact …

[HTML][HTML] Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics

R Fevre, G Mary, N Vertti-Quintero, A Durand… - Iscience, 2023 - cell.com
Culturing and screening cells in microfluidics, particularly in three-dimensional formats, has
the potential to impact diverse areas from fundamental biology to cancer precision medicine …

Technological advances in tumor-on-chip technology: From bench to bedside

S Bērziņa, A Harrison, V Taly, W Xiao - Cancers, 2021 - mdpi.com
Simple Summary Various 3D in vitro tumor models are rapidly advancing cancer research.
Unlike animal models, they can be produced quickly and are amenable to high-throughput …

Nanoplasmonic single‐tumoroid microarray for real‐time secretion analysis

YC Liu, S Ansaryan, J Tan, N Broguiere… - Advanced …, 2024 - Wiley Online Library
Organoid tumor models have emerged as a powerful tool in the fields of biology and
medicine as such 3D structures grown from tumor cells recapitulate better tumor …

Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids

V Bonnet, E Maikranz, M Madec… - Proceedings of the …, 2024 - National Acad Sciences
Evaluating the ability of cytotoxic T lymphocytes (CTLs) to eliminate tumor cells is crucial, for
instance, to predict the efficiency of cell therapy in personalized medicine. However, the …

High-speed large-scale 4D activities mapping of moving C. elegans by deep-learning-enabled light-field microscopy on a chip

T Zhu, L Zhu, Y Li, X Chen, M He, G Li, H Zhang… - Sensors and Actuators B …, 2021 - Elsevier
We report a novel fusion of microfluidics and light-field microscopy, to achieve high-speed
4D (space+ time) imaging of moving C. elegans on a chip. Our approach combines …

3D Cell Culture Method in Channel‐Free Water‐in‐Oil Droplets

SJ Bae, SH Choi, DJ Im - Small Methods, 2024 - Wiley Online Library
A new channel‐free water‐in‐oil (WO) droplet 3D cell culture method is proposed to address
the challenges while maintaining the advantages of the conventional 3D cell culture …