[HTML][HTML] Current trends in toxicity assessment of herbal medicines: A narrative review

A Jităreanu, A Trifan, M Vieriu, IC Caba, I Mârțu… - Processes, 2022 - mdpi.com
Even in modern times, the popularity level of medicinal plants and herbal medicines in
therapy is still high. The World Health Organization estimates that 80% of the population in …

Toxicogenomics and systems toxicology: aims and prospects

MD Waters, JM Fostel - Nature Reviews Genetics, 2004 - nature.com
Toxicogenomics combines transcript, protein and metabolite profiling with conventional
toxicology to investigate the interaction between genes and environmental stress in disease …

[HTML][HTML] Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide

R Mesnage, G Renney, GE Séralini, M Ward… - Scientific reports, 2017 - nature.com
The impairment of liver function by low environmentally relevant doses of glyphosate-based
herbicides (GBH) is still a debatable and unresolved matter. Previously we have shown that …

Biologic monitoring of exposure to environmental chemicals throughout the life stages: requirements and issues for consideration for the National Children's Study

DB Barr, RY Wang, LL Needham - Environmental Health …, 2005 - ehp.niehs.nih.gov
Biomonitoring of exposure is a useful tool for assessing environmental exposures. The
matrices available for analyses include blood, urine, breast milk, adipose tissue, and saliva …

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

JC Lindon, HC Keun, TMD Ebbels, JMT Pearce… - …, 2005 - Taylor & Francis
The utility of metabonomics in the evaluation of xenobiotic toxicity has been
comprehensively assessed by the Consortium for Metabonomic Toxicology (COMET) …

[HTML][HTML] Ecotoxicogenomic approaches for understanding molecular mechanisms of environmental chemical toxicity using aquatic invertebrate, Daphnia model …

HJ Kim, P Koedrith, YR Seo - International Journal of Molecular Sciences, 2015 - mdpi.com
Due to the rapid advent in genomics technologies and attention to ecological risk
assessment, the term “ecotoxicogenomics” has recently emerged to describe integration of …

Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology

WHM Heijne, AS Kienhuis, B Van Ommen… - Expert review of …, 2005 - Taylor & Francis
Toxicogenomics can facilitate the identification and characterization of toxicity, as illustrated
in this review. Toxicogenomics, the application of the functional genomics technologies …

Pesticides and cancer: insights into toxicoproteomic-based findings

J George, Y Shukla - Journal of proteomics, 2011 - Elsevier
Humans are often exposed to a variety of pollutants that contribute to an individual's risk for
diseases including cancer. Animal, cell cultures and epidemiological lines of evidence …

Studies on glyphosate-induced carcinogenicity in mouse skin: a proteomic approach

J George, S Prasad, Z Mahmood, Y Shukla - Journal of proteomics, 2010 - Elsevier
Glyphosate is a widely used broad spectrum herbicide, reported to induce various toxic
effects in non-target species, but its carcinogenic potential is still unknown. Here we showed …

Metabonomic modeling of drug toxicity

HC Keun - Pharmacology & therapeutics, 2006 - Elsevier
Global metabolic profiling (metabonomics/metabolomics) has shown particular promise in
the area of toxicology and drug development. In both preclinical screening and mechanistic …