Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches
J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
Computational exploration and design of a multi-epitopes vaccine construct against Chlamydia psittaci
AM Alsubaiyel, SI Bukhari - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Chlamydia psittaci is an intracellular pathogen and causes variety of deadly infections in
humans. Antibiotics are effective against C. psittaci however high percentage of resistant …
humans. Antibiotics are effective against C. psittaci however high percentage of resistant …
Designing a novel multi-epitopes pan-vaccine against SARS-CoV-2 and seasonal influenza: in silico and immunoinformatics approach
M Fathollahi, H Motamedi, H Hossainpour… - Journal of …, 2023 - Taylor & Francis
The merger of COVID-19 and seasonal influenza infections is considered a potentially
serious threat to public health. These two viral agents can cause extensive and severe lower …
serious threat to public health. These two viral agents can cause extensive and severe lower …
In silico designed novel multi-epitope mRNA vaccines against Brucella by targeting extracellular protein BtuB and LptD
J Shi, Y Zhu, Z Yin, Y He, Y Li, G Haimiti, X Xie… - Scientific Reports, 2024 - nature.com
Brucella, a gram-negative intracellular bacterium, causing Brucellosis, a zoonotic disease
with a range of clinical manifestations, from asymptomatic to fever, fatigue, loss of appetite …
with a range of clinical manifestations, from asymptomatic to fever, fatigue, loss of appetite …
In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation
R Sundararaj, A Mathimaran, D Prabhu… - Scientific Reports, 2024 - nature.com
Direct exposure to the fungal species Alternaria alternata is a major risk factor for the
development of asthma, allergic rhinitis, and inflammation. As of November 23rd 2020, the …
development of asthma, allergic rhinitis, and inflammation. As of November 23rd 2020, the …
Identification of the shared hub gene signatures and molecular mechanisms between HIV-1 and pulmonary arterial hypertension
H Mai, X Yang, Y Xie, J Zhou, Y Wei, T Luo, J Yang… - Scientific Reports, 2024 - nature.com
The close link between HIV-1 infection and the occurrence of pulmonary arterial
hypertension (PAH). However, the underlying molecular mechanisms of their interrelation …
hypertension (PAH). However, the underlying molecular mechanisms of their interrelation …
Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a
significant threat to human life, and current BCG vaccinations only provide sporadic …
significant threat to human life, and current BCG vaccinations only provide sporadic …
Construction of an aerolysin-based multi-epitope vaccine against Aeromonas hydrophila: an in silico machine learning and artificial intelligence-supported approach
AS Alawam, MS Alwethaynani - Frontiers in Immunology, 2024 - frontiersin.org
Aeromonas hydrophila, a gram-negative coccobacillus bacterium, can cause various
infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis …
infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis …
Identification of potential vaccine targets for elicitation of host immune cells against SARS-CoV-2 by reverse vaccinology approach
The COVID-19 pandemic has emerged as a critical global health crisis, demanding urgent
and effective strategies for containment. While some knowledge exists about epitope …
and effective strategies for containment. While some knowledge exists about epitope …
Protein profiling and immunoinformatic analysis of the secretome of a metal-resistant environmental isolate Pseudomonas aeruginosa S-8
The bacterial secretome represents a comprehensive catalog of proteins released
extracellularly that have multiple important roles in virulence and intercellular …
extracellularly that have multiple important roles in virulence and intercellular …