The study of pain development has come into its own. Reaping the rewards of years of
developmental and molecular biology, it has now become possible to translate fundamental …

Objective To develop evidence-based guidelines for preventing or treating neonatal pain
and its adverse consequences. Compared with older children and adults, neonates are …

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different
CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy …

Primary open angle glaucoma is a common eye disease characterized by loss of the axons
of the retinal ganglion cells leading to progressive loss of vision. The site of damage to the …

Human preterm neonates are subjected to repetitive pain during neonatal intensive care.
We hypothesized that exposure to repetitive neonatal pain may cause permanent or long …

Invasive procedures that would be painful in children and adults are frequently performed on
infants admitted to the neonatal intensive care unit. This article discusses sensory responses …

The mechanisms by which infants and children process pain should be viewed within the
context of a developing sensory nervous system. The study of the neurophysiological …

The dorsal horn of the spinal cord in the newborn rat is characterized by large cutaneous
mechanoreceptive fields, a predominance of A‐fibre synaptic inputs and diffuse primary …

The cutaneous flexion reflex has been used to study spinal sensory processing in 68 infants
(37 female, 31 male) aged between 28 and 42 weeks postconceptional age (PCA) …

Objectives: To describe developmentally appropriate, specific body movements and other
biobehavioral responses of preterm infants to a group of routine care giving tasks (Clustered …