Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

[HTML][HTML] Beneficial attributes and adverse effects of major plant-based foods anti-nutrients on health: A review

H Nath, M Samtiya, T Dhewa - Human Nutrition & Metabolism, 2022 - Elsevier
Anti-nutrients are the biomolecules that if present in food along with nutrients, can reduce
either the absorption or the utilization of nutrients. The physiological importance of anti …

From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment

A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Oligomeric proanthocyanidins: an updated review of their natural sources, synthesis, and potentials

F Nie, L Liu, J Cui, Y Zhao, D Zhang, D Zhou, J Wu, B Li… - Antioxidants, 2023 - mdpi.com
Oligomeric Proanthocyanidins (OPCs), as a class of compounds widely found in plants, are
particularly abundant in grapes and blueberries. It is a polymer comprising many different …

[HTML][HTML] Dietary natural products as a potential inhibitor towards advanced glycation end products and hyperglycemic complications: A phytotherapy approaches

M Vijaykrishnaraj, K Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Natural products exist in various natural foods such as plants, herbs, fruits, and vegetables.
Furthermore, marine life offers potential natural products with significant biological activity …

Antioxidants for the treatment of retinal disease: summary of recent evidence

P Wang, EK Chin, D Almeida - Clinical Ophthalmology, 2021 - Taylor & Francis
Retinal tissue is prone to oxidant burden and oxidative stress secondary to the generation of
reactive oxygen species from high metabolic demand. The formation of reactive oxygen …

Proanthocyanidins attenuate the high glucose‐induced damage of retinal pigment epithelial cells by attenuating oxidative stress and inhibiting activation of the NLRP3 …

H Li, R Li, L Wang, D Liao, W Zhang… - Journal of biochemical …, 2021 - Wiley Online Library
Diabetic retinopathy (DR) is a common diabetic complication known to cause vision
impairment and blindness. Previous studies have demonstrated that proanthocyanidins …

Role of oral antioxidant supplementation in the current management of diabetic retinopathy

EA Alfonso-Muñoz… - International journal of …, 2021 - mdpi.com
Oxidative stress has been postulated as an underlying pathophysiologic mechanism of
diabetic retinopathy (DR), the main cause of avoidable blindness in working-aged people …

Genetic and Transcriptomic Background of Oxidative Stress and Antioxidative Therapies in Late Complications of Type 2 Diabetes Mellitus: A Systematic Review

G Tonin, V Dolžan, J Klen - Antioxidants, 2024 - mdpi.com
This systematic review extensively investigated the role of the genetic and transcriptomic
factors in late complications of type 2 diabetes mellitus (T2DM) and the current approaches …

Effects of flavonoid supplementation on common eye disorders: A systematic review and meta-analysis of clinical trials

S Davinelli, S Ali, G Scapagnini, C Costagliola - Frontiers in nutrition, 2021 - frontiersin.org
Background: Emerging studies show that certain plant compounds may reduce the severity
of most prevalent ocular abnormalities. The aim of this systematic review and meta-analysis …