Histones are integral components of eukaryotic chromatin that have a pivotal role in the
organization and function of the genome. The dynamic regulation of chromatin involves the …

Abstract Broad‐complex, Tramtrack, and Bric‐à‐brac/poxvirus and zinc finger (BTB/POZ) is
a conserved domain found in many eukaryotic proteins with diverse cellular functions …

Abstract BTB (bric-a-brack, Tramtrack, and broad complex) is a diverse group of protein-
protein interaction domains found within metazoan proteins. Transcription factors contain a …

Although BTB–zinc finger (BTB-ZF) transcription factors control the differentiation of multiple
hematopoietic and immune lineages, how they function is poorly understood. The BTB-ZF …

The main protease of severe acute respiratory syndrome coronavirus 2, Mpro, is a key viral
protein essential for viral infection and replication. Mpro has been the target of many …

MCF7 is a commonly used luminal type A non-invasive/poor-invasive human breast cancer
cell line that does not usually migrate or invade compared with MDA-MB-231 highly …

Zinc Finger DNA‐binding domain‐containing proteins are the most populous family among
eukaryotic transcription factors. Among these, members of the BTB domain‐containing ZBTB …

Background Histone cell cycle regulator (HIRA) complex is an important histone chaperone
that mediates the deposition of the H3. 3 histone variant onto chromatin independently from …

The cellular response to hypoxia is mainly governed by a transcription factor, hypoxia-
inducible factor 1 (HIF-1). Although upregulation of HIF-1 target genes has been …

Abstract Hypoxia-inducible factor 1 (HIF-1), recognized as a master transcription factor for
adaptation to hypoxia, is associated with malignant characteristics and therapy resistance in …