Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

The course of immune maturation has evolved to favour survival at each stage of
development in early life. Fetal and neonatal immune adaptations facilitate intrauterine …

Viral infections during pregnancy can have devastating consequences on pregnancy
outcomes, fetal development, and maternal health. In this review, we examine fetal and …

Infections at the maternal-fetal interface can directly harm the fetus and induce complications
that adversely impact pregnancy outcomes. Innate immune signaling by both fetal-derived …

The incidence of type 1 diabetes has increased since the mid-twentieth century at a rate that
is too rapid to be attributed to genetic predisposition alone. While the disease can occur at …

Human cytomegalovirus (HCMV) is a ubiquitous herpes virus (human herpes virus 5) with
the highest morbidity and mortality rates compared to other herpes viruses. Risk groups …

BACKGROUND Cytomegalovirus (CMV) is the most common intrauterine infection, leading
to infant brain damage. Prognostic assessment of CMV-infected fetuses has remained an …

Human cytomegalovirus (CMV) infection of the developing fetus can result in adverse
pregnancy outcomes including death in utero. Fetal injury results from direct viral cytopathic …

Cytomegalovirus is the most common congenital infection causing serious disease in
infants. It is the leading infectious cause of sensorineural hearing loss and …