Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Mural cells are essential components of blood vessels and are necessary for normal
development, homeostasis, and organ function. Alterations in mural cell density or the stable …

Abstracts The Angiopoietin/Tie system acts as a vascular specific ligand/receptor system to
control endothelial cell survival and vascular maturation. The Angiopoietin family includes …

Simple Summary The dissemination of cancer cells from their original location to distant
organs where they grow, a process called metastasis, causes more than 90% of cancer …

Despite genetic evidence establishing angiopoietin-1 (Ang-1) as an essential regulator of
vascular development, the molecular mechanisms underlying Ang-1 function are almost …

Angiogenesis is required for normal embryonic vascular development and aberrant
angiogenesis contributes to several diseases, including cancer, diabetes and tissue …

Interactions between endothelial cells (ECs) and perivascular mural cells (MCs) via
signaling molecules or physical contacts are implicated both in vascular remodeling and …

Development of a suitable mouse model would facilitate the investigation of
pathomechanisms underlying human psoriasis and would also assist in development of …

Abstract Angiopoietins (ANG-1 and ANG-2) and their TIE-2 receptor tyrosine kinase have
wide-ranging effects on tumor malignancy that includes angiogenesis, inflammation, and …

The field of tissue engineering seeks to create metabolically demanding, functional tissues,
which will require blood vessel networks capable of forming rapidly in a variety of …