BACKGROUND After recognition of its pivotal contribution to fetomaternal tolerance, the
study of galectin-1 (gal-1) functions in the context of pregnancy became an attractive topic in …

CA153 was originally discovered as a tumor antigen recognized by two monoclonal
antibodies DF3 and 115D8 simultaneously. Subsequent studies showed that DF3 …

Ovarian cancer is the leading cause of cancer deaths in female patients. The current
therapeutics in ovarian cancer are limited and inefficient in curing the disease. To tackle this …

Simple Summary Early cancer detection is a challenge in treating cancer patients.
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …

Immunotherapy was first investigated as a therapeutic option for treating cancer more than a
century ago. During this period, it has gone through numerous disappointments when the …

Hypercalciuria is a major risk factor for nephrolithiasis. We previously reported that
Uromodulin (UMOD) protects against nephrolithiasis by upregulating the renal calcium …

Platinum-based agents are the main treatment option in ovarian cancer (OC). Herein, we
report a poly (lactic-co-glycolic acid)(PLGA) nanoparticle (NP) encapsulating platinum (II) …

Ovarian granulosa cell tumors (GCTs) are thought to arise from cells of the ovarian follicle
and comprise a rare entity of ovarian masses. We recently identified the G-protein-coupled …

Background Human serum MUC1 peptide fragments bearing aberrant O-glycans are
secreted from columnar epithelial cell surfaces and known as clinically important serum …

Trace amine-associated receptor 1 (TAAR1) is a Gαs-protein coupled receptor that plays an
important role in the regulation of the immune system and neurotransmission in the CNS. In …