Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …

The role of aldo‐keto reductase family 1 member B1 (AKR1B1) in cancer is not totally clear
but growing evidence is suggesting to have a great impact on cancer progression. AKR1B1 …

The analysis of cell-free DNA (cfDNA) in plasma provides information on pathological
processes in the body. Blood cfDNA is in the form of nucleosomes, which maintain their …

Inhibin subunit beta A (INHBA) is a member of the transforming growth factor-beta (TGF-β)
superfamily that plays a fundamental role in various cancers. However, a systematic …

Recently, tumor immunotherapy based on immune checkpoint inhibitors (ICI) has been
introduced and widely adopted for various tumor types. Nevertheless, tumor immunotherapy …

Vitamin D regulates a plethora of physiological processes in the human body and has been
proposed to exert several anticancer effects. Epigenetics plays an important role in …

DNA methylation occurs when a methyl group is added to a cytosine (C) residue's fifth
carbon atom, forming 5-methylcytosine (5-mC). Cancer genomes have a distinct methylation …

Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis,
prognosis and therapeutic monitoring of CRC depends largely on tissue biopsy. However …

Cancer morbidity and mortality are growing rapidly worldwide and it is urgent to develop a
convenient and effective method that can identify cancer patients at an early stage and …