This review article summarizes the relevant English literature on gout from 2010 through
April 2017. It emphasizes that the current epidemiology of gout indicates a rising prevalence …

There has been increased interest in gout in both academic and clinical practice settings.
Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen …

Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed.
New data on imaging and clinical diagnosis have become available since the first EULAR …

Urate is the end-product of the purine metabolism in humans. The dominant source of urate
is endogenous purines and the remainder comes through diet. Approximately two thirds of …

Background The aim of this study was to compare the frequency and volume of dual energy
CT (DECT) urate deposits in people with asymptomatic hyperuricaemia and symptomatic …

The advent of computed tomography (CT) has revolutionized radiology. Starting as head-
only scanners, modern CT systems are now capable of performing whole-body …

Xanthine oxidase inhibitors such as allopurinol and febuxostat have been the mainstay
urate-lowering therapy (ULT) for treating hyperuricaemia in patients with gout. However, not …

The current widely used clinical staging system for hyperuricaemia and gout describes the
symptomatology of gout, but does not capture key aspects of the pathological basis of the …

Background Gout is a chronic disease of monosodium urate (MSU) crystal deposition.
Although hyperuricaemia is the central risk factor for development of gout, not all people with …

Multiple interacting checkpoints are involved in the pathophysiology of gout. Hyperuricemia
is the key risk factor for gout and is considered a prerequisite for monosodium urate (MSU) …