MCP-1: Function, regulation, and involvement in disease
S Singh, D Anshita, V Ravichandiran - International immunopharmacology, 2021 - Elsevier
Abstract MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif)
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …
[HTML][HTML] Macrophages: the good, the bad, and the gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …
sterile inflammation. In this review, we will compile and interpret recent findings on the …
Macrophage heterogeneity in the context of rheumatoid arthritis
IA Udalova, A Mantovani, M Feldmann - Nature Reviews Rheumatology, 2016 - nature.com
Macrophages are very important in the pathogenesis of rheumatoid arthritis (RA). The
increase in the number of sublining macrophages in the synovium is an early hallmark of …
increase in the number of sublining macrophages in the synovium is an early hallmark of …
The pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The Pathogenesis of Rheumatoid Arthritis | NEJM Skip to main content NEJM Group Follow Us
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
The many facets of macrophages in rheumatoid arthritis
E Siouti, E Andreakos - Biochemical pharmacology, 2019 - Elsevier
Macrophages are central to the pathophysiology of rheumatoid arthritis (RA). They constitute
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis
DE Sanford, BA Belt, RZ Panni, A Mayer… - Clinical cancer …, 2013 - AACR
Purpose: To determine the role of the CCL2/CCR2 axis and inflammatory monocytes
(CCR2+/CD14+) as immunotherapeutic targets in the treatment of pancreatic cancer …
(CCR2+/CD14+) as immunotherapeutic targets in the treatment of pancreatic cancer …
Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric …
EK Moon, C Carpenito, J Sun, LCS Wang, V Kapoor… - Clinical cancer …, 2011 - AACR
Purpose: Adoptive T-cell immunotherapy with tumor infiltrating lymphocytes or genetically-
modified T cells has yielded dramatic results in some cancers. However, T cells need to …
modified T cells has yielded dramatic results in some cancers. However, T cells need to …
Role of cytokines in rheumatoid arthritis
M Feldmann, FM Brennan… - Annual review of …, 1996 - annualreviews.org
▪ Abstract Analysis of cytokine mRNA and protein in rheumatoid arthritis tissue revealed that
many proinflammatory cytokines such as TNFα, IL-1, IL-6, GM-CSF, and chemokines such …
many proinflammatory cytokines such as TNFα, IL-1, IL-6, GM-CSF, and chemokines such …
[HTML][HTML] T cell migration in rheumatoid arthritis
M Mellado, L Martínez-Muñoz, G Cascio… - Frontiers in …, 2015 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …
Chemokines
BJ Rollins - Blood, The Journal of the American Society of …, 1997 - ashpublications.org
Address reprint requests to Barrett J. Rollins, MD, PhD, Dana-kines than humans (for
example, there is no clear-cut murine Farber Cancer Institute, 44 Binney St, Boston, MA …
example, there is no clear-cut murine Farber Cancer Institute, 44 Binney St, Boston, MA …