Docetaxel: An update on its molecular mechanisms, therapeutic trajectory and nanotechnology in the treatment of breast, lung and prostate cancer
Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …
Versatile function of NF-ĸB in inflammation and cancer
Q Ma, S Hao, W Hong, V Tergaonkar, G Sethi… - … Hematology & Oncology, 2024 - Springer
Nuclear factor-kappaB (NF-ĸB) plays a crucial role in both innate and adaptive immune
systems, significantly influencing various physiological processes such as cell proliferation …
systems, significantly influencing various physiological processes such as cell proliferation …
Long circulating photoactivable nanomicelles with tumor localized activation and ROS triggered self-accelerating drug release for enhanced locoregional chemo …
Although chemo-photodynamic therapy demonstrates promising synergetic therapeutic
effect in malignant cancers, the currently available nanocarriers offer the limited capabilities …
effect in malignant cancers, the currently available nanocarriers offer the limited capabilities …
[HTML][HTML] Engineered nanoparticles as emerging gene/drug delivery systems targeting the nuclear factor-κB protein and related signaling pathways in cancer
R Eskandani, M Kazempour, R Farahzadi… - Biomedicine & …, 2022 - Elsevier
The transcription factor nuclear factor-κB (NF-κB) is a critical regulator of the immune
response, inflammation, cell growth, and survival. Canonical and non-canonical pathways …
response, inflammation, cell growth, and survival. Canonical and non-canonical pathways …
Application of star poly (ethylene glycol) derivatives in drug delivery and controlled release
X Zhao, J Si, D Huang, K Li, Y Xin, M Sui - Journal of Controlled Release, 2020 - Elsevier
Multi-arm star poly (ethylene glycol)(PEG) polymers have a number of advantages over
linear PEG polymers when used as carriers for drug delivery and controlled release. For …
linear PEG polymers when used as carriers for drug delivery and controlled release. For …
Docetaxel-loaded nanoformulations delivery for breast cancer management: Challenges, recent advances, and future perspectives
Breast cancer (BC) is a major health and financial hardship globally, and conventional
chemotherapy has bounded success in thoroughly treating the disease. It can result in …
chemotherapy has bounded success in thoroughly treating the disease. It can result in …
Human serum albumin-poly (Lactide)-conjugated self-assembly NPs for targeted docetaxel delivery and improved therapeutic efficacy in oral cancer
Oral cancer is one of the most prevalent malignancies worldwide. Here, to prepare a
biocompatible tumor-targeted nanoformulation capable of efficient loading of the …
biocompatible tumor-targeted nanoformulation capable of efficient loading of the …
Multifaceted role of NF-κB in hepatocellular carcinoma therapy: Molecular landscape, therapeutic compounds and nanomaterial approaches
R Gupta, MM Kadhim, AT Jalil, AM Obayes… - Environmental …, 2023 - Elsevier
The predominant kind of liver cancer is hepatocellular carcinoma (HCC) that its treatment
have been troublesome difficulties for physicians due to aggressive behavior of tumor cells …
have been troublesome difficulties for physicians due to aggressive behavior of tumor cells …
pH-sensitive nanoparticles codelivering docetaxel and dihydroartemisinin effectively treat breast cancer by enhancing reactive oxidative species-mediated …
Tumor growth and metastasis are the major causes of high mortality in breast cancer. We
previously constructed pH-sensitive nanoparticles (D/D NPs) for the codelivery of docetaxel …
previously constructed pH-sensitive nanoparticles (D/D NPs) for the codelivery of docetaxel …
Metal–organic framework nanoparticles for arsenic trioxide drug delivery
R Ettlinger, M Sönksen, M Graf, N Moreno… - Journal of Materials …, 2018 - pubs.rsc.org
Arsenic trioxide is a double-edged sword: On the one hand it is known as a poison, on the
other hand it is used as an anticancer drug. Though effective in the treatment of leukaemia …
other hand it is used as an anticancer drug. Though effective in the treatment of leukaemia …