Architecture of bacterial respiratory chains

VRI Kaila, M Wikström - Nature Reviews Microbiology, 2021 - nature.com
Bacteria power their energy metabolism using membrane-bound respiratory enzymes that
capture chemical energy and transduce it by pumping protons or Na+ ions across their cell …

Oxygen Activation and Energy Conservation by Cytochrome c Oxidase

M Wikström, K Krab, V Sharma - Chemical reviews, 2018 - ACS Publications
This review focuses on the type A cytochrome c oxidases (C c O), which are found in all
mitochondria and also in several aerobic bacteria. C c O catalyzes the respiratory reduction …

The electron–proton bottleneck of photosynthetic oxygen evolution

P Greife, M Schönborn, M Capone, R Assunção… - Nature, 2023 - nature.com
Photosynthesis fuels life on Earth by storing solar energy in chemical form. Today's oxygen-
rich atmosphere has resulted from the splitting of water at the protein-bound manganese …

The coupling mechanism of mammalian respiratory complex I

D Kampjut, LA Sazanov - Science, 2020 - science.org
INTRODUCTION Complex I is the first and, with 45 subunits and a total mass of~ 1 MDa, the
most elaborate of the mitochondrial electron transfer chain enzymes. Complex I converts …

Cryo-EM structure of the entire mammalian F-type ATP synthase

G Pinke, L Zhou, LA Sazanov - Nature structural & molecular biology, 2020 - nature.com
The majority of adenosine triphosphate (ATP) powering cellular processes in eukaryotes is
produced by the mitochondrial F1Fo ATP synthase. Here, we present the atomic models of …

A universal coupling mechanism of respiratory complex I

V Kravchuk, O Petrova, D Kampjut… - Nature, 2022 - nature.com
Complex I is the first enzyme in the respiratory chain, which is responsible for energy
production in mitochondria and bacteria. Complex I couples the transfer of two electrons …

Molecular dynamics simulations of membrane permeability

RM Venable, A Kramer, RW Pastor - Chemical reviews, 2019 - ACS Publications
This Review illustrates the evaluation of permeability of lipid membranes from molecular
dynamics (MD) simulation primarily using water and oxygen as examples. Membrane …

Atomic structure of the entire mammalian mitochondrial complex I

K Fiedorczuk, JA Letts, G Degliesposti, K Kaszuba… - Nature, 2016 - nature.com
Mitochondrial complex I (also known as NADH: ubiquinone oxidoreductase) contributes to
cellular energy production by transferring electrons from NADH to ubiquinone coupled to …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

The coupling mechanism of mammalian mitochondrial complex I

J Gu, T Liu, R Guo, L Zhang, M Yang - Nature Structural & Molecular …, 2022 - nature.com
Mammalian respiratory complex I (CI) is a 45-subunit, redox-driven proton pump that
generates an electrochemical gradient across the mitochondrial inner membrane to power …