Background The androgen receptor (AR) is expressed frequently in breast cancer, but its
prognostic significance is unclear. Preclinical data suggest that expression of AR may …

Androgen receptor (AR) signaling exerts an antiestrogenic, growth-inhibitory influence in
normal breast tissue, and this role may be sustained in estrogen receptor α (ERα)-positive …

Introduction The androgen receptor (AR) is widely expressed in breast cancers and has
been proposed as a therapeutic target in estrogen receptor alpha (ER) negative breast …

Animal models of cancer have been instrumental in advancing our understanding of the
biology of tumor initiation and progression, in studying gene function and in performing …

Background Androgen receptor (AR) is a promising therapeutic target for breast cancer.
However, its prognostic value remains controversial in triple negative breast cancer (TNBC) …

The androgen receptor (AR) is a drug target in breast cancer, and AR-targeted therapies
have induced tumor responses in breast cancer patients. In this review, we summarized the …

Androgen receptor (AR, a member of the steroid hormone receptor family) status has
become increasingly important as both a prognostic marker and potential therapeutic target …

The androgen receptor (AR) is expressed in the majority of breast cancer and across the
three main breast cancer subtypes. Historically, the oncogenic role of AR has best been …

Steroid hormone receptors (SRs) have a multitude of functions in human biology and
disease progression. The SR family of related ligand-activated transcription factors includes …

To characterize prognostic values of androgen receptor (AR) in triple-negative (TN) breast
cancers, we investigated AR expression status and levels, explored an association of AR …