Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health

WJY Chee, SY Chew, LTL Than - Microbial cell factories, 2020 - Springer
Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

Urinary tract infections: the current scenario and future prospects

G Mancuso, A Midiri, E Gerace, M Marra, S Zummo… - Pathogens, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide,
occurring in both community and healthcare settings. Although the clinical symptoms of UTIs …

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Ö Baltekin, A Boucharin, E Tano… - Proceedings of the …, 2017 - National Acad Sciences
The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect
prescription and use of antibiotics. A core problem is that there is no sufficiently fast …

Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - Am Soc Microbiol
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

New and developing diagnostic technologies for urinary tract infections

M Davenport, KE Mach, LMD Shortliffe… - Nature Reviews …, 2017 - nature.com
Timely and accurate identification and determination of the antimicrobial susceptibility of
uropathogens is central to the management of UTIs. Urine dipsticks are fast and amenable …

Cell‐based delivery systems: emerging carriers for immunotherapy

Z Li, Y Wang, Y Ding, L Repp… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

“It takes a village”: mechanisms underlying antimicrobial recalcitrance of polymicrobial biofilms

G Orazi, GA O'Toole - Journal of Bacteriology, 2019 - Am Soc Microbiol
Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …

Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer

E Shrestha, JR White, SH Yu, I Kulac… - The Journal of …, 2018 - auajournals.org
Purpose: Studies demonstrating bacterial DNA and cultivable bacteria in urine samples
have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate …

Gardnerella vaginalis as a Cause of Bacterial Vaginosis: Appraisal of the Evidence From in vivo Models

S Morrill, NM Gilbert, AL Lewis - Frontiers in cellular and infection …, 2020 - frontiersin.org
Koch's postulates dictate the use of experimental models to illustrate features of human
disease and provide evidence for a singular organism as the cause. The underlying cause …

Antimicrobial capacity of plant polyphenols against gram-positive bacteria: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán… - Current medicinal …, 2020 - ingentaconnect.com
Background: Multi-drug-resistant bacteria such as Methicillin-Resistant Staphylococcus
aureus (MRSA) disseminate rapidly amongst patients in healthcare facilities and suppose …