Therapeutic potential of pyrrole and pyrrolidine analogs: an update
N Jeelan Basha, SM Basavarajaiah, K Shyamsunder - Molecular Diversity, 2022 - Springer
The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …
been a versatile field of study for a long time for its diverse biological and medicinal …
Physiological and pharmaceutical considerations for rectal drug formulations
S Hua - Frontiers in pharmacology, 2019 - frontiersin.org
Although the oral route is the most convenient route for drug administration, there are a
number of circumstances where this is not possible from either a clinical or pharmaceutical …
number of circumstances where this is not possible from either a clinical or pharmaceutical …
Advancements in rectal drug delivery systems: clinical trials, and patents perspective
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
Catalyst- and Oxidizing Reagent-Free Electrochemical Benzylic C(sp3)–H Oxidation of Phenol Derivatives
ZW Hou, MM Zhang, WC Yang… - The Journal of Organic …, 2022 - ACS Publications
A site-selective electrochemical approach for the benzylic C (sp3)–H oxidation reaction of
phenol derivatives along with hydrogen evolution has been developed. The protocol …
phenol derivatives along with hydrogen evolution has been developed. The protocol …
Achievements in thermosensitive gelling systems for rectal administration
M Bialik, M Kuras, M Sobczak, E Oledzka - International Journal of …, 2021 - mdpi.com
Rectal drug delivery is an effective alternative to oral and parenteral treatments. This route
allows for both local and systemic drug therapy. Traditional rectal dosage formulations have …
allows for both local and systemic drug therapy. Traditional rectal dosage formulations have …
Thermoresponsive mucoadhesive hybrid gels in advanced drug delivery systems
Thermoresponsive polymers have seen extensive use in the development of stimuli-
responsive drug formulations for oral, buccal, nasal, ocular, topical, rectal, parenteral, and …
responsive drug formulations for oral, buccal, nasal, ocular, topical, rectal, parenteral, and …
Transmucosal drug administration as an alternative route in palliative and end-of-life care during the COVID-19 pandemic
Abstract The Coronavirus disease 2019 (COVID-19) pandemic has led to a surge in need for
alternative routes of administration of drugs for end of life and palliative care, particularly in …
alternative routes of administration of drugs for end of life and palliative care, particularly in …
[HTML][HTML] pH-sensitive in situ gel of mirtazapine Invasomes for rectal drug delivery: Protruded bioavailability and anti-depressant efficacy
The present research emphasizes fabrication alongside the assessment of an innovative
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …
Formulation and optimization of theophylline-loaded enteric-coated spanlastic nanovesicles for colon delivery; Ameliorate acetic acid-induced ulcerative colitis
Abstract Treatment of colon diseases presents one of the most significant obstacles to drug
delivery due to the inability to deliver sufficient drug concentration selectively to the colon …
delivery due to the inability to deliver sufficient drug concentration selectively to the colon …
Formulation, and optimization of transdermal Atorvastatin Calcium-Loaded Ultra-flexible vesicles; ameliorates poloxamer 407-caused dyslipidemia
MA Akl, S Ryad, MF Ibrahim, AA Kassem - International Journal of …, 2023 - Elsevier
Atorvastatin calcium (AC), a cholesterol-lowering medication, has limited oral bioavailability
(14%) and adverse impacts on the gastrointestinal tract (GIT), liver, and muscle. So, in an …
(14%) and adverse impacts on the gastrointestinal tract (GIT), liver, and muscle. So, in an …