Cellular stress is an intrinsic part of cell physiology that underlines cell survival or death. The
ability of mammalian cells to regulate global protein synthesis (aka translational control) …

A large number of signalling pathways converge on p53 to induce different cellular stress
responses that aim to promote cell cycle arrest and repair or, if the damage is too severe, to …

High temperatures adversely impact productivity and quality (nutritional and functional) of
wheat grains. Anthesis and post-anthesis developmental stages are more sensitive to heat …

Short upstream open reading frames (uORFs) are cis-acting elements located within the 5′-
leader sequence of transcripts and are defined by an initiation codon in-frame with a …

The SARS-CoV-2 infection generates up to nine different sub-genomic mRNAs (sgRNAs), in
addition to the genomic RNA (gRNA). The 5′ UTR of each viral mRNA shares the first 75 …

The SOCS family are key negative regulators of cytokine and growth factor signaling.
Typically, 8–17 SOCS genes are present in vertebrate species with eight known in …

Background The beneficial effect of thermogenic adipocytes in maintaining body weight and
protecting against metabolic disorders has raised interest in understanding the regulatory …

Microproteins encoded by small open reading frames (sORFs) have emerged as a
fascinating frontier in genomics. Traditionally overlooked due to their small size, recent …

Due to the increasing impact of worldwide environmental changes, temperature stress has
become a major factor resulting in crop yield losses. The discovery of temperature‐stress …

The mechanistic/mammalian target of rapamycin (mTOR) is a conserved serine/threonine
kinase that integrates cellular signals from the nutrient and energy status to act, namely, on …