To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics

NJ Kurganovs, N Engedal - Frontiers in Pharmacology, 2024 - frontiersin.org
Around 1 in 7 men will be diagnosed with prostate cancer during their lifetime. Many strides
have been made in the understanding and treatment of this malignancy over the years …

Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

W Wei, X Gao, J Qian, L Li, C Zhao, L Xu, Y Zhu… - The Journal of Clinical …, 2024 - jci.org
Proper control of inflammatory responses is essential for embryonic development, but the
underlying mechanism is poorly understood. Here, we show that under physiological …

miR-137 regulates autophagy and apoptosis in duodenal ulcer by targeting BNIP3L

Z Pan, L Zhang, J Hu - Medicine, 2024 - journals.lww.com
Background: Duodenal ulcer (DU) represents a clinical manifestation and disease state that
occurs when the mucosal surface of the duodenum is damaged. The processes of …

BECLIN-1 is Essential for the Maintenance of Gastrointestinal Epithelial Integrity by Regulating Endocytic Trafficking, F-actin Organization and Lysosomal Function

J Juliani, S Tran, TJ Harris, P De Cruz, SL Ellis… - bioRxiv, 2024 - biorxiv.org
Disrupted intestinal homeostasis and barrier function are key contributors to the
development of various diseases, including inflammatory bowel disease (IBD). BECLIN-1, a …

La pérdida del cilio primario inducida por ácido palmítico disocia el complejo PKD2-BECN1 inhibiendo la autofagia en neuronas POMC

CA García Navarrete - 2024 - repositorio.uchile.cl
La autofagia es un proceso crucial para la proteostasis, y diversas proteínas participan en
su regulación. Beclin-1 es una proteína fundamental para la biogénesis del autofagosoma …