Ultrasound-responsive nanocarriers in cancer treatment: A review
The safe and effective delivery of anticancer agents to diseased tissues is one of the
significant challenges in cancer therapy. Conventional anticancer agents are generally …
significant challenges in cancer therapy. Conventional anticancer agents are generally …
Recent advances with liposomes as pharmaceutical carriers
VP Torchilin - Nature reviews Drug discovery, 2005 - nature.com
Liposomes—microscopic phospholipid bubbles with a bilayered membrane structure—have
received a lot of attention during the past 30 years as pharmaceutical carriers of great …
received a lot of attention during the past 30 years as pharmaceutical carriers of great …
Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair
Because of poor engraftment and safety concerns regarding mesenchymal stem cell (MSC)
therapy, MSC-derived exosomes have emerged as an alternative cell-free therapy for …
therapy, MSC-derived exosomes have emerged as an alternative cell-free therapy for …
Iron oxide nanoparticles augment the intercellular mitochondrial transfer–mediated therapy
T Huang, T Zhang, X Jiang, A Li, Y Su, Q Bian… - Science …, 2021 - science.org
The transfer of mitochondria between cells has recently been revealed as a spontaneous
way to protect the injured cells. However, the utilization of this natural transfer process for …
way to protect the injured cells. However, the utilization of this natural transfer process for …
Ligand-targeted therapeutics in anticancer therapy
TM Allen - Nature Reviews Cancer, 2002 - nature.com
Cytotoxic chemotherapy or radiotherapy of cancer is limited by serious, sometimes life-
threatening, side effects that arise from toxicities to sensitive normal cells because the …
threatening, side effects that arise from toxicities to sensitive normal cells because the …
Multifunctional nanocarriers
VP Torchilin - Advanced drug delivery reviews, 2006 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …
Improving the endosomal escape of cell-penetrating peptides and their cargos: strategies and challenges
A Erazo-Oliveras, N Muthukrishnan, R Baker… - Pharmaceuticals, 2012 - mdpi.com
Cell penetrating peptides (CPPs) can deliver cell-impermeable therapeutic cargos into cells.
In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis …
In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis …
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases
PS Low, WA Henne… - Accounts of chemical …, 2008 - ACS Publications
In order to avoid the toxicities associated with prescription drug use today, we have explored
novel methods for delivering drugs selectively to pathologic cells, thereby avoiding the …
novel methods for delivering drugs selectively to pathologic cells, thereby avoiding the …
Folate-mediated delivery of macromolecular anticancer therapeutic agents
Y Lu, PS Low - Advanced drug delivery reviews, 2002 - Elsevier
The receptor for folic acid constitutes a useful target for tumor-specific drug delivery,
primarily because:(1) it is upregulated in many human cancers, including malignancies of …
primarily because:(1) it is upregulated in many human cancers, including malignancies of …
Peptide-functionalized liposomes as therapeutic and diagnostic tools for cancer treatment
Clinically efficacious medication in anticancer therapy has been successfully designed with
liposome-based nanomedicine. The liposomal formulation in cancer drug delivery can be …
liposome-based nanomedicine. The liposomal formulation in cancer drug delivery can be …