Inflammation and neuroinflammation play critical roles in the pathogenesis of
neurodegenerative diseases such as Parkinson's disease (PD). Nanomaterials with reactive …

The COVID-19 mRNA vaccine was developed by the scalable manufacture of lipid
nanoparticles (LNPs) that encapsulate mRNA within the lipid. There are many potential …

Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

Introduction A major challenge in treating central nervous system (CNS) disorders is to
achieve adequate drug delivery across the blood–brain barrier (BBB). Receptor-mediated …

Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

Ischemic stroke is a complex, high-mortality disease with multifactorial etiology and
pathogenesis. Currently, drug therapy is mainly used treat ischemic stroke in clinic, but there …

Treatment of glioblastoma (GBM) remains challenging due to the presence of blood–brain
barrier (BBB) and tumor heterogeneity. Herein, Au nanosheets (AuNSs) functionalized with …

Monogenic disorders refer to a group of human diseases caused by mutations in single
genes. While disease-modifying therapies have offered some relief from symptoms and …

Recently, neurological disorders have led to a growing global burden of fatalities and
disabilities. The limited capacity for natural self‐regeneration poses a significant challenge …

With the increasing number of patients suffering from central nervous system (CNS)
diseases, there is a pressing demand to acquire dependable diagnostic tools in the early …