PI3K/Akt/mTOR Signaling Pathway as a Target for Colorectal Cancer Treatment
PD Leiphrakpam, C Are - International journal of molecular sciences, 2024 - mdpi.com
In the last decade, pathway-specific targeted therapy has revolutionized colorectal cancer
(CRC) treatment strategies. This type of therapy targets a tumor-vulnerable spot formed …
(CRC) treatment strategies. This type of therapy targets a tumor-vulnerable spot formed …
[HTML][HTML] Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors
R Liu, J Zhou, X Chen, J Zhang, Q Chen, X Liu, K Yao - Biomedicines, 2024 - mdpi.com
Gastrointestinal tumors present a significant challenge for precision medicine due to their
complexity, necessitating the development of more specific diagnostic tools and therapeutic …
complexity, necessitating the development of more specific diagnostic tools and therapeutic …
Association Between RAS/BRAF Mutations and Complete Response Following Total Neoadjuvant Therapy in Patients with Rectal Cancer: A Prospective …
Background The impact of RAS/BRAF mutation on primary response rates after total
neoadjuvant therapy (TNT) in patients with advanced rectal cancer is unclear. The aim of …
neoadjuvant therapy (TNT) in patients with advanced rectal cancer is unclear. The aim of …
Preserving or peeling the inferior mesenteric arterial sheath during laparoscopic rectal cancer surgery: a prospective study of surgical outcomes
Q Li, Y Wang, J Wang, L Qian, S Wang, T Cao, Y Xia… - BMC surgery, 2023 - Springer
Background We mainly evaluated whether preserving the inferior mesenteric artery (IMA)
sheath to dissecting IMA root lymph nodes (also called No. 253 lymph nodes) would benefit …
sheath to dissecting IMA root lymph nodes (also called No. 253 lymph nodes) would benefit …
ENO1 deletion potentiates ferroptosis and decreases glycolysis in colorectal cancer cells via AKT/STAT3 signaling
Y Liu, Y Hou, F Zhang, X Wang - Experimental and …, 2024 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most prevailing and lethal forms of cancer globally. α‑
enolase (ENO1) has been well documented to be involved in the progression and drug …
enolase (ENO1) has been well documented to be involved in the progression and drug …
Expression Analysis of VPS72 and Associated Biological Behaviors in Colon Cancer
J Cao, H Zhang, X Xie, W Wang - International Journal of General …, 2024 - Taylor & Francis
Background VPS72 is highly expressed in hepatocellular carcinoma and prostate cancer,
participating in various cellular processes such as gene transcription, replication, DNA …
participating in various cellular processes such as gene transcription, replication, DNA …
CacyBP/SIP knockdown inhibits cell cycle process of colon cancer by suppressing CDK8-mediated Wnt/β-catenin signaling pathway
HJ Liang, J Ge, HL Lin, ZY Liu, F Gu, JY Zhu, ZY Li… - 2023 - researchsquare.com
Background Previously, we found that calcyclin-binding or siah-1-interacting protein
(CacyBP/SIP) promotes colon cancer proliferation. However, the potential mechanism has …
(CacyBP/SIP) promotes colon cancer proliferation. However, the potential mechanism has …