Glutamatergic dysfunction in Schizophrenia
AO Kruse, JR Bustillo - Translational Psychiatry, 2022 - nature.com
The NMDA-R hypofunction model of schizophrenia started with the clinical observation of
the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or …
the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or …
Non-coding RNA in the wiring and remodeling of neural circuits
M Soutschek, G Schratt - Neuron, 2023 - cell.com
The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
Recent insights into the roles of circular RNAs in human brain development and neurologic diseases
S Najafi, SMA Zarch, J Majidpoor, S Pordel… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …
RNA transcripts characterized with a closed loop structure making them resistant to …
CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer
X Wang, J Li, X Bian, C Wu, J Hua… - Proceedings of the …, 2021 - National Acad Sciences
Circular RNAs (circRNAs) have emerged as key regulators of human cancers, yet their
modes of action in gastric cancer (GC) remain largely unknown. Here, we identified circURI1 …
modes of action in gastric cancer (GC) remain largely unknown. Here, we identified circURI1 …
Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation
While most of the efforts to uncover mechanisms contributing to bipolar disorder (BD)
focused on phenotypes at the mature neuron stage, little research has considered events …
focused on phenotypes at the mature neuron stage, little research has considered events …
A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after …
Traumatic brain injury (TBI) can lead to different neurological and psychiatric disorders.
Circular RNAs (circRNAs) are highly expressed in the nervous system and enriched in …
Circular RNAs (circRNAs) are highly expressed in the nervous system and enriched in …
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Little is known about circular RNAs (circRNAs) in specific brain cells and human
neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed …
neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed …
Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers
Abstract Non-coding RNAs (ncRNAs), including microRNAs, circular RNAs, and long non-
coding RNAs, are important regulators of normal biological processes and their abnormal …
coding RNAs, are important regulators of normal biological processes and their abnormal …
Differentially expressed circular RNAs in peripheral blood mononuclear cells of patients with Parkinson's disease
S Ravanidis, A Bougea, D Karampatsi… - Movement …, 2021 - Wiley Online Library
Background New noninvasive and affordable molecular approaches that will complement
current practices and increase the accuracy of Parkinson's disease (PD) diagnosis are …
current practices and increase the accuracy of Parkinson's disease (PD) diagnosis are …
NOVA2 regulates neural circRNA biogenesis
D Knupp, DA Cooper, Y Saito, RB Darnell… - Nucleic Acids …, 2021 - academic.oup.com
Circular RNAs (circRNAs) are highly expressed in the brain and their expression increases
during neuronal differentiation. The factors regulating circRNAs in the developing mouse …
during neuronal differentiation. The factors regulating circRNAs in the developing mouse …