T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas

A Zernecke, H Winkels, C Cochain… - Circulation …, 2020 - Am Heart Assoc
The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

An assessment of the toxicity of polypropylene microplastics in human derived cells

J Hwang, D Choi, S Han, J Choi, J Hong - Science of the Total Environment, 2019 - Elsevier
Environmental pollution caused by plastic waste is a growing global problem. Discarded
plastic products and debris (microplastic particles) in the oceans detrimentally affect marine …

The immunology of atherosclerosis

A Gisterå, GK Hansson - Nature reviews nephrology, 2017 - nature.com
Cardiovascular disease is the leading cause of death worldwide, both in the general
population and among patients with chronic kidney disease (CKD). In most cases, the …

Evaluation of potential toxicity of polyethylene microplastics on human derived cell lines

R Gautam, JH Jo, M Acharya, A Maharjan… - Science of the Total …, 2022 - Elsevier
Microplastics bare of major concern for environmental conservation and animal welfare in
recent years as its use has increased tremendously. Polyethylene microplastics (PE-MPs) …

Macrophage phenotype and function in different stages of atherosclerosis

I Tabas, KE Bornfeldt - Circulation research, 2016 - Am Heart Assoc
The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …

Inflammation and plaque vulnerability

GK Hansson, P Libby, I Tabas - Journal of internal medicine, 2015 - Wiley Online Library
Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at
sites of blood flow disturbance. The disease usually remains silent until a breakdown of …

The role of T cells in age-related diseases

E Carrasco, MM Gómez de las Heras… - Nature Reviews …, 2022 - nature.com
Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting
in aberrant T cell-driven cytokine and cytotoxic responses that ultimately cause tissue …

Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

The role of inflammasomes in vascular cognitive impairment

L Poh, WL Sim, DG Jo, QN Dinh, GR Drummond… - Molecular …, 2022 - Springer
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …