The lateral hypothalamus is comprised of a heterogeneous mix of neurons that serve to
integrate and regulate sleep, feeding, stress, energy balance, reward, and motivated …

Peroxisome proliferator‐activated receptor (PPAR) group includes three isoforms encoded
by PPARG, PPARA, and PPARD genes. High concentrations of PPARs are found in parts of …

Psychological trauma and obesity co-occur frequently and have been identified as major risk
factors for psychiatric disorders. Surprisingly, preclinical studies examining how obesity …

Diabetes mellitus (DM) is a chronic metabolic disease that may comorbid with various
psychiatric disorders, such as anxiety and depression. The search for effective therapeutics …

High neuroticism is related to cardiovascular morbidity. Early detection of metabolic and
cardiovascular risk is important in high-risk groups to enable preventive measures. The aim …

Modulation between sleep and wake states is controlled by a number of heterogeneous
neuron populations. Due to the topological proximity and genetic co-localization of the …

Preclinical studies suggest the implication of the adipocyte hormone leptin in anxiety and
fear processes. We explored for potential differences regarding plasma leptin, cortisol and …

设计的评价范式, 是介于活体和细胞测定之间的药物筛选模型. 该模型从小鼠迷宫实验模型发展
而来, 在行为测试的便捷性上具有一定优势. 斑马鱼与人类具有较高的基因同源性 …

Одной из проблем современной геномики является поиск ключевых систем, которые
позволяли бы корректировать и получать желательные фенотипы. Особое значение …

Background: Stress is a major contributor to various health issues, including depression,
anorexia nervosa, diabetes, and obesity. Rauwolfia serpentina, a traditional medicinal plant …