The dynamic and multicellular processes of neuroinflammation are mediated by the
nonneuronal cells of the central nervous system, which include astrocytes and the brain's …

Histone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are
involved in gene transcription and regulation, cell proliferation, differentiation, migration, and …

Abstract Fluorine-18 (t ½= 109.7 min) is the most commonly used isotope to prepare
radiopharmaceuticals for molecular imaging by positron emission tomography (PET) …

Alzheimer's disease (AD) is characterized by memory loss and decline of cognitive function,
associated with progressive neurodegeneration. While neuropathological processes like …

Over the past decade the process of inflammation has been a focus of increasing interest in
the Alzheimer's disease (AD) field, not only for its potential role in neuronal degeneration but …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common
cause of dementia among the elderly population. The good correlation of the density and …

Microglial activation has been linked with deficits in neuronal function and synaptic plasticity
in Alzheimer's disease (AD). The mitochondrial translocator protein (TSPO) is known to be …

Abstract Glycogen synthase kinase‐3 (GSK‐3) regulates multiple cellular processes in
diabetes, oncology, and neurology. N‐(3‐(1H‐1, 2, 4‐triazol‐1‐yl) propyl)‐5‐(3‐chloro‐4 …

Abstract Background High-profile Phase 3 clinical trials of bapineuzumab and solanezumab,
antibodies targeted at amyloid-beta (Aβ) removal, have failed to meet their primary …

Neuroinflammation is thought to play a pivotal role in many diseases affecting the brain,
including Alzheimer's disease, multiple sclerosis and stroke. Neuroinflammation is …