DNA methylation is a conserved epigenetic modification that is important for gene regulation
and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental …

Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …

Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

Epigenetic modifications of the genome are generally stable in somatic cells of multicellular
organisms. In germ cells and early embryos, however, epigenetic reprogramming occurs on …

Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family
members regulate the release of proteins from the space between the mitochondrial inner …

Active DNA demethylation is involved in many vital developmental and physiological
processes of plants and animals. Recent genetic and biochemical studies in Arabidopsis …

Most of the transcription factors (TFs) responsible for controlling seed development are not
yet known. To identify TF genes expressed at specific stages of seed development, including …

Parent-of-origin-specific (imprinted) gene expression is regulated in Arabidopsis thaliana
endosperm by cytosine demethylation of the maternal genome mediated by the DNA …

DNA methylation is an epigenetic mark associated with transposable element silencing and
gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the …

Cells of the early mammalian embryo, including pluripotent embryonic stem (ES) cells and
primordial germ cells (PGCs), are epigenetically dynamic and heterogeneous. During early …