[HTML][HTML] Temporal patterning of the vertebrate developing neural tube

A Sagner - Current Opinion in Genetics & Development, 2024 - Elsevier
Highlights•A shared temporal transcription factor code may orchestrate neuronal subtype
specification in large regions of the developing nervous system.•Temporal identity correlates …

A brain-wide map of descending inputs onto spinal V1 interneurons

PD Chapman, AS Kulkarni, AJ Trevisan, K Han… - Neuron, 2024 - cell.com
Motor output results from the coordinated activity of neural circuits distributed across multiple
brain regions that convey information to the spinal cord via descending motor pathways. Yet …

[HTML][HTML] The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output

AJ Trevisan, K Han, P Chapman, AS Kulkarni… - …, 2024 - pmc.ncbi.nlm.nih.gov
Neural circuits in the spinal cord are composed of diverse sets of interneurons that play
crucial roles in shaping motor output. Despite progress in revealing the cellular architecture …

[HTML][HTML] Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis

D Vijatovic, FA Toma, ZPM Harrington, C Sommer… - …, 2024 - pmc.ncbi.nlm.nih.gov
Vertebrates exhibit a wide range of motor behaviors, ranging from swimming to complex
limb-based movements. Here we take advantage of frog metamorphosis, which captures a …

[HTML][HTML] Synaptic imbalance and increased inhibition impair motor function in SMA

EV Fletcher, JI Chalif, TM Rotterman, JG Pagiazitis… - …, 2024 - pmc.ncbi.nlm.nih.gov
Movement is executed through the balanced action of excitatory and inhibitory
neurotransmission in motor circuits of the spinal cord. Short-term perturbations in one of the …

Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish

SB Rojas - 2024 - search.proquest.com
In vertebrates, spinal interneurons are essential for the initiation and propagation of
locomotor activity with each class of interneurons serving its own unique role. Ipsilateral …