Spirocyclic pyrrolidines are structural motifs frequently found in a wide variety of natural
products, pharmaceuticals and biologically significant compounds. In the past few years …

3-Amino-2-oxindoles bearing tetra-substituted stereocenter are very important constituents
of many bioactive and pharmaceutical agents. In the last few years, asymmetric …

Catalytic asymmetric construction of the biologically important spiro [pyrrolidin‐3, 2′‐
oxindole] scaffold with contiguous quaternary stereogenic centers in excellent …

N-2, 2, 2-Trifluoroethylisatin ketimines with β-trifluoromethyl enones, 3-trifluoroethylidene
oxindole, and 3-trifluoroethylidene benzofuranone can undergo asymmetric [3+ 2] …

Phosphine‐catalyzed enantioselective annulation reactions involving ketimines are a
daunting synthetic challenge owing to the intrinsic low reactivity of ketimine substrates. A …

An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-
isothiocyanato oxindoles and 3-nitroindoles has been disclosed. A wide range of …

A new strategy for the construction of optically active 5′-CF3 spiro [pyrrolidin-3, 2′-
oxindole] was described. A series of unprecedented 1, 3-dipoles were obtained by …

The 1, 3-dipolar cycloaddition of azomethine ylides derived from substituted isatins and 1, 3-
thiazolane-4-carboxylic acid to a series of 2-(arylmethylene)-2, 3-dihydro-1H-inden-1-ones …

Spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrid compounds were obtained
in excellent yields from the regio-and stereoselective reaction between β-nitrostyrenes and …

An efficient synthesis of 1-methyl-3-[(E)-arylmethylidene] tetrahydro-4 (1H)-pyridinones was
achieved by the reaction of 1-methyl-4-piperidone and aromatic aldehydes in the presence …