[HTML][HTML] The styrene–maleic acid copolymer: a versatile tool in membrane research

JM Dörr, S Scheidelaar, MC Koorengevel… - European Biophysics …, 2016 - Springer
A new and promising tool in membrane research is the detergent-free solubilization of
membrane proteins by styrene–maleic acid copolymers (SMAs). These amphipathic …

Bioapplications of RAFT polymerization

C Boyer, V Bulmus, TP Davis, V Ladmiral, J Liu… - Chemical …, 2009 - ACS Publications
A living radical polymerization (LRP) is a free radical polymerization that aims at displaying
living character,(ie, does not terminate or transfer and is able to continue polymerization …

Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance

A Shapira, YD Livney, HJ Broxterman… - Drug resistance updates, 2011 - Elsevier
Anticancer drug resistance almost invariably emerges and poses major obstacles towards
curative therapy of various human malignancies. In the current review we will distinguish …

Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor

Q Yin, J Shen, Z Zhang, H Yu, Y Li - Advanced drug delivery reviews, 2013 - Elsevier
Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …

Standing on the shoulders of Hermann Staudinger: Post‐polymerization modification from past to present

KA Günay, P Theato, HA Klok - Journal of Polymer Science Part …, 2013 - Wiley Online Library
With a span as long as the history of polymer science itself, post‐polymerization modification
represents a versatile platform for the preparation of diversely functionalized polymers from …

Multi-stimuli sensitive amphiphilic block copolymer assemblies

A Klaikherd, C Nagamani… - Journal of the American …, 2009 - ACS Publications
Stimuli-responsive polymers are arguably the most widely considered systems for a variety
of applications in biomedical arena. We report here a novel triple stimuli sensitive block …

Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery

DJ Gary, N Puri, YY Won - Journal of Controlled Release, 2007 - Elsevier
Gene therapy holds tremendous promise in the treatment of many genetic and acquired
diseases. The future of gene therapy in humans, however, is contingent upon the discovery …

Development of a novel endosomolytic diblock copolymer for siRNA delivery

AJ Convertine, DSW Benoit, CL Duvall… - Journal of controlled …, 2009 - Elsevier
The gene knockdown activity of small interfering RNA (siRNA) has led to their use as target
validation tools and as potential therapeutics for a variety of diseases. The delivery of these …

PEG-SS-PPS: reduction-sensitive disulfide block copolymer vesicles for intracellular drug delivery

S Cerritelli, D Velluto, JA Hubbell - Biomacromolecules, 2007 - ACS Publications
Under appropriate conditions, block copolymeric macroamphiphiles will self-assemble in
water to form vesicles, referred to as polymersomes. We report here polymersomes that can …

Chitosan oligosaccharide-based dual pH responsive nano-micelles for targeted delivery of hydrophobic drugs

Y Wang, A Khan, Y Liu, J Feng, L Dai, G Wang… - Carbohydrate …, 2019 - Elsevier
In this study, chitosan oligosaccharide (COS)-vanillin imine (COS-Vani Imine)-based dual
pH responsive nano-micelles (DPRNs) were synthesized. The resultant DPRNs were used …