Critical Assessment of the Prospects of Quorum-Quenching Therapy for Staphylococcus aureus Infection

M Otto - International Journal of Molecular Sciences, 2023 - mdpi.com
Staphylococcus aureus is an important pathogen that causes a high number of infections
and is one of the leading causes of death in hospitalized patients. Widespread antibiotic …

Quorum sensing inhibition and antibiofilm action of triterpenoids: An updated insight

SP Bhattacharya, S Karmakar, K Acharya… - Fitoterapia, 2023 - Elsevier
Abstract Development of biofilm is a protective strategy for invading bacterial pathogens
against host immune response and administered antimicrobials. Quorum sensing (QS) …

Peptidomimetics as potential anti-virulence drugs against resistant bacterial pathogens

OF Martínez, HM Duque, OL Franco - Frontiers in Microbiology, 2022 - frontiersin.org
The uncontrollable spread of superbugs calls for new approaches in dealing with microbial-
antibiotic resistance. Accordingly, the anti-virulence approach has arisen as an attractive …

Structure-dependent activity of plant natural products against methicillin-resistant Staphylococcus aureus

C Moreno Cardenas, SS Çiçek - Frontiers in microbiology, 2023 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major causes for
nosocomial infections and has been classified as “high priority pathogen” by the World …

[HTML][HTML] Anti-quorum sensing effects of medicinal plants and chemical compounds: A new dimension against Pseudomonas aeruginosa and Staphylococcus aureus

KC Nwachukwu, OC Ugbogu, IL Nwosu… - … of Microbiology and …, 2023 - jmidonline.org
Quorum sensing (QS) is a communication mechanism utilized by microorganisms to
deliberately unleash virulence factors for their survival in living or non-living hosts. Biofilm …

Trends in Quorum Sensing and Quorum Quenching

A Kodaparthi, SB Bastipati - 2023 - books.rsc.org
Aquatic and terrestrial microenvironments from a wide range of biological systems are go-to
places for microbial communities. 1, 2 Microorganisms acquire a strong ability to adapt to a …

Learning from Nature: Naturally Derived Remedies

M Suzuki - Antibiofilm Strategies: Current and Future Applications …, 2022 - Springer
The rise and spread of antimicrobial resistance among microbes represents one of today's
most pressing global health issues. To combat the antimicrobial resistance of pathogens, the …

Triterpenoids and saponins in drug discovery

J Liu, C Wang, Q Wang, W Zhang, Z Li, S He… - Privileged Scaffolds in …, 2023 - Elsevier
Triterpenoids, an important group of secondary metabolites, are widely distributed naturally
in plants in a free form or in the form of glycosides or esters, including tetracyclic …

Integrating QQ with Nano-techniques–A Potent Antibacterial Therapy

S Munagala, M Dunna, C Tulasi, B Sowmya, B Archana… - 2023 - books.rsc.org
For a very long period, it was considered that bacteria, unlike eukaryotic species, acted as
independent individuals and adhered to a unicellular lifestyle. 1 During infections, the mass …

[HTML][HTML] Using Automation For Antimicrobial Screening

T Sandle - drugdiscoveryonline.com
As has been widely reported, the rise in antimicrobial resistant microorganisms presents a
major global health challenge. Many pathogens have developed multi-drug resistant strains …