Innovative tools for mechanobiology: unraveling outside-in and inside-out mechanotransduction

D Mohammed, M Versaevel, C Bruyère… - … in Bioengineering and …, 2019 - frontiersin.org
Cells and tissues can sense and react to the modifications of the physico-chemical
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …

[HTML][HTML] Cell monolayers sense curvature by exploiting active mechanics and nuclear mechanoadaptation

M Luciano, SL Xue, WH De Vos, L Redondo-Morata… - Nature Physics, 2021 - nature.com
The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …

Actomyosin contractility scales with myoblast elongation and enhances differentiation through YAP nuclear export

C Bruyère, M Versaevel, D Mohammed, L Alaimo… - Scientific reports, 2019 - nature.com
Skeletal muscle fibers are formed by the fusion of mononucleated myoblasts into long linear
myotubes, which differentiate and reorganize into multinucleated myofibers that assemble in …

Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites

M Versaevel, JB Braquenier, M Riaz, T Grevesse… - Scientific reports, 2014 - nature.com
Increasing evidences show that the actin cytoskeleton is a key parameter of the nuclear
remodeling process in response to the modifications of cellular morphology. However …

[HTML][HTML] Substrate area confinement is a key determinant of cell velocity in collective migration

D Mohammed, G Charras, E Vercruysse, M Versaevel… - Nature Physics, 2019 - nature.com
Collective cell migration is fundamental throughout development, during wound healing and
in many diseases. Although much effort has focused on cell–cell junctions, a role for …

Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury

T Grevesse, BE Dabiri, KK Parker, S Gabriele - Scientific reports, 2015 - nature.com
Although pathological changes in axonal morphology have emerged as important features
of traumatic brain injury (TBI), the mechanical vulnerability of the axonal microcompartment …

Matrix stiffness modulates formation and activity of neuronal networks of controlled architectures

J Lantoine, T Grevesse, A Villers, G Delhaye… - Biomaterials, 2016 - Elsevier
The ability to construct easily in vitro networks of primary neurons organized with imposed
topologies is required for neural tissue engineering as well as for the development of …

Tumorigenic mesenchymal clusters are less sensitive to moderate osmotic stresses due to low amounts of junctional E-cadherin

D Mohammed, CY Park, JJ Fredberg, DA Weitz - Scientific Reports, 2021 - nature.com
The migration of tumorigenic cells is a critical step for metastatic breast cancer progression.
Although the role of the extracellular matrix in breast cancer cell migration has been …

Comparative study of the aging behavior of plasma activated hexamethyldisiloxane-based plasma polymers and silicone elastomer thin films

T Egghe, R Ghobeira, R Morent, R Hoogenboom… - Progress in Organic …, 2022 - Elsevier
The aging of plasma activated plasma polymer films has been studied to a limited extent,
despite the recent application-oriented interest for these coatings. Therefore, the aging of …

Carbon dots/silicone rubber composites for fluorescence detection of biodiesel in fuel blends

E Koken, HB Sonmez - Materials Chemistry and Physics, 2023 - Elsevier
Carbon-based nanoparticles, specifically carbon quantum dots (CQDs), have received
growing interest significantly owing to their optical characteristics and production simplicity …