MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint

BAH Smith, A Deutzmann, KM Correa… - Proceedings of the …, 2023 - National Acad Sciences
The Siglecs (sialic acid-binding immunoglobulin-like lectins) are glycoimmune checkpoint
receptors that suppress immune cell activation upon engagement of cognate sialoglycan …

Determination of monosaccharide composition in human serum by an improved HPLC method and its application as candidate biomarkers for endometrial cancer

Y Chen, Q Yao, X Zeng, C Hao, X Li, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Altered glycan levels in serum have been associated with increased risk of cancer. In this
study, we have developed and validated a HPLC-based method to analyze monosaccharide …

[HTML][HTML] Bacillus subtilis HW2 enhances growth performance and alleviates gut injury via attenuation of endoplasmic reticulum stress and regulation of gut microbiota …

P Chen, H Lv, M Du, W Liu, C Che, J Zhao, H Liu - Poultry Science, 2024 - Elsevier
This study investigated the effects of Bacillus subtilis HW2 on the growth performance,
immune response, endoplasmic reticulum (ER) stress, and intestinal health in broilers with …

Robustness in glycosylation systems: effect of modified monosaccharides, acceptor decoys and azido sugars on cellular nucleotide-sugar levels and pattern of N …

V Del Solar, R Gupta, Y Zhou, G Pawlowski… - Molecular omics, 2020 - pubs.rsc.org
Small molecule monosaccharide analogs (eg 4F-GlcNAc, 4F-GalNAc) and acceptor decoys
(eg ONAP, SNAP) are commonly used as metabolic glycoengineering tools to perturb …

Optical fiber sensor for glycoprotein detection based on localized surface plasmon resonance of discontinuous Ag-deposited nanostructure

Z Samavati, A Samavati, AF Ismail, MA Rahman… - Optical Fiber …, 2021 - Elsevier
A combination of the optical fiber technology and the art of material miniaturization provides
a label-free glycoprotein sensor with an excellent range of detection. This study examines …

[图书][B] Discovery and Characterization of Glyco-Immune Checkpoints

BAH Smith - 2021 - search.proquest.com
Glycans are complex polysaccharides that decorate the surface of every cell in the human
body and have functions spanning many essential aspects of cell and organismal biology …

[引用][C] Yulong Chen1, 2, Qin Yao1, 2, Xuan Zeng3, Cui Hao2, Xiulian Li4, Lijuan Zhang2 and Pengjiao Zeng2

Y Chen, Q Yao, X Zeng, C Hao, X Li, L Zhang, P Zeng - 2022 - europepmc.org
The American Cancer Society estimates that 65,950 new endometrial cancer (EC) cases will
be diagnosed in 2022 and 12,550 will succumb to this dreadful disease. It is estimated that …