During a screen of bacterial nutrients as inhibitors of Escherichia coli O157: H7 biofilm, the
Prüß research team made an intriguing observation: among 95 carbon and 95 nitrogen …

By using O-benzoyl hydroxylamines as amine sources, the first convenient copper-catalyzed
electrophilic amination of sodium sulfinates has been realized. Even with 2 mol% catalyst …

Oxadiazole bearing compounds are one of the most attractive class for researchers due to
their biological activities. In the undertaken research, a number of N-substituted derivatives …

New thiopurines with the propargylthio, pyrrolidinobutynylthio, sulfenamide, and
sulfonamide groups in the pyrimidine ring were synthesized. The anticancer activity of these …

Sulfonamide or sulfa drug is a known term used in various classes of medicines. Due to the
high efficiency of sulfonamide group in various drugs candidates, it is still used as a vital …

Purpose: To evaluate the enzyme inhibition activity of N-substituted sulfamoyl derivatives of
2-amino-1-phenylethane as probable new drug candidates for the treatment of Alzheimer's …

Two novel metal complexes, that is, Ni (StmAn) 2 (4) and Cu (StmAn) 2 (5), were
synthesized from unsymmetrical Schiff base ligand StmAn (3). The ligand was prepared by …

Objectives Due to various biological activities of sulfonamides, a series of new N-(5-chloro-2-
methoxyphenyl)-aryl sulfonamides (3a–e) and their N-benzyl/ethyl substituted derivatives …

Proline racemases (PRAC), catalyzing the l‐proline and d‐proline interconversion, are
essential factors in eukaryotic pathogens such as Trypanosoma cruzi, Trypanosoma vivax …

Abstract ω-[(4 Z)-2-Aryl-4-arylmethylidene-5-oxo-4, 5-dihydro-1 H-imidazol-1-yl] alkanoic
acids were synthesized by reaction of N-substituted α, β-dehydropeptides with chloro …