[HTML][HTML] S100 protein family in human cancer

H Chen, C Xu, Z Liu - American journal of cancer research, 2014 - ncbi.nlm.nih.gov
S100 protein family has been implicated in multiple stages of tumorigenesis and
progression. Among the S100 genes, 22 are clustered at chromosome locus 1q21, a region …

New perspectives on S100 proteins: a multi-functional Ca 2+-, Zn 2+-and Cu 2+-binding protein family

CW Heizmann, JA Cox - Biometals, 1998 - Springer
Abstract S100 proteins (16 members) show a very divergent pattern of cell-and tissue-
specific expression, of subcel-lular localizations and relocations, of post-translational …

[HTML][HTML] Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sjögren's syndrome patients

S Steinfeld, E Cogan, LS King, P Agre, R Kiss… - Laboratory …, 2001 - Elsevier
Patients with Sjögren's syndrome (SS) suffer from deficient secretion of saliva due to an
autoimmune destruction of salivary glands, however, glandular dysfunction also occurs …

S100 family proteins in inflammation and beyond

G Sreejit, MC Flynn, M Patil, P Krishnamurthy… - Advances in clinical …, 2020 - Elsevier
The S100 family proteins possess a variety of intracellular and extracellular functions. They
interact with multiple receptors and signal transducers to regulate pathways that govern …

[HTML][HTML] S100A gene family: immune-related prognostic biomarkers and therapeutic targets for low-grade glioma

Y Zhang, X Yang, XL Zhu, H Bai, ZZ Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: Despite the better prognosis given by surgical resection and chemotherapy in
low-grade glioma (LGG), progressive transformation is still a huge concern. In this case, the …

S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9

M Saleem, MH Kweon, JJ Johnson… - Proceedings of the …, 2006 - National Acad Sciences
We previously showed that the calcium-binding protein S100A4 is overexpressed during the
progression of prostate cancer (CaP) in humans and in the TRAMP (transgenic …

Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease

C Pilette, V Godding, R Kiss, M Delos… - American journal of …, 2001 - atsjournals.org
The epithelial polymeric immunoglobulin receptor/transmembrane secretory component
(pIgR/SC) transports into secretions polymeric immunoglobulin A (pIgA), which is …

Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry

SA Schwartz, RJ Weil, RC Thompson, Y Shyr… - Cancer research, 2005 - AACR
Clinical diagnosis and treatment decisions for a subset of primary human brain tumors,
gliomas, are based almost exclusively on tissue histology. Approaches for glioma diagnosis …

Protein S100A4: too long overlooked by pathologists?

L Mazzucchelli - The American journal of pathology, 2002 - ASIP
Invasion and metastasis are hallmarks of malignant tumors resulting from the interaction
between tumor cells and the surrounding tissues. They include pathogenic steps, such as …

Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate …

I Camby, N Belot, S Rorive, F Lefranc… - Brain …, 2001 - Wiley Online Library
Galectins, a family of mammalian lectins with specificity to β‐galactosides, are involved in
growth‐regulatory mechanisms and cell adhesion. A relationship is assumed to exist …