Acute stroke is associated with high morbidity and mortality. In the last decades, new
therapies have been investigated with the aim of improving clinical outcomes in the acute …

Pressure autoregulation is an important hemodynamic mechanism that protects the brain
against inappropriate fluctuations in cerebral blood flow in the face of changing cerebral …

Abstract Introduction Pressure-reactivity index (PRx) is a useful tool in brain monitoring of
trauma patients, but the question remains about its critical values. Using our TBI database …

Background and Purpose—Delayed cerebral ischemia (DCI) is a recognized contributor to
unfavorable outcome after subarachnoid hemorrhage (SAH). Recent data challenge the …

Background A previous retrospective single-centre study suggested that the percentage of
time spent with cerebral perfusion pressure (CPP) below the individual lower limit of …

Impaired cerebrovascular reactivity in adult moderate and severe traumatic brain injury (TBI)
is known to be associated with worse global outcome at 6–12 months. As technology has …

Introduction Sepsis-associated delirium (SAD) increases morbidity in septic patients and,
therefore, factors contributing to SAD should be further characterized. One possible …

Current neurointensive care guidelines recommend intracranial pressure (ICP) and cerebral
perfusion pressure (CPP) centered management for moderate-severe traumatic brain injury …

BACKGROUND: Cerebrovascular pressure reactivity is the principal mechanism of cerebral
autoregulation. Assessment of cerebral autoregulation can be performed by using the mean …

Cerebral autoregulation, as measured using the pressure reactivity index (PRx), has been
related to global patient outcome in adult patients with traumatic brain injury (TBI). To date …