Over the last three decades, virus-like particles (VLPs) have evolved to become a widely
accepted technology, especially in the field of vaccinology. In fact, some VLP-based …

During the last decade, the spectre of an influenza pandemic of avian origin has led to a
revision of national and global pandemic preparedness plans and has stressed the need for …

We have developed an eight-plasmid DNA transfection system for the rescue of infectious
influenza A virus from cloned cDNA. In this plasmid-based expression system, viral cDNA is …

We describe a new reverse-genetics system that allows one to efficiently generate influenza
A viruses entirely from cloned cDNAs. Human embryonic kidney cells (293T) were …

For influenza virus, we developed an efficient, noncytotoxic, plasmid-based virus-like
particle (VLP) system to reflect authentic virus particles. This system was characterized …

To get insights into the role played by each of the influenza A virus polypeptides in
morphogenesis and virus particle assembly, the generation of virus-like particles (VLPs) has …

Influenza virus transcription occurs in the nuclei of infected cells, where the viral genomic
RNAs are complexed with a nucleoprotein (NP) to form ribonucleoprotein (RNP) structures …

The genome of lymphocytic choriomeningitis virus (LCMV) consists of two negative-sense
single-stranded RNA segments, designated L and S. Both segments contain two viral genes …

Avian influenza viruses represent a growing threat for an influenza pandemic. To develop
recombinant vaccine for avian influenza of the H9N2 subtype, we expressed in insect cells …

The cytoplasmic tail of the influenza A virus M2 protein is highly conserved among influenza
A virus isolates. The cytoplasmic tail appears to be dispensable with respect to the ion …