Most nitroaromatic compounds are toxic and mutagenic for living organisms, but some
microorganisms have developed oxidative or reductive pathways to degrade or transform …

Considerable support exists for the roles of metabolism in modulating the carcinogenic
properties of chemicals. In particular, many of these compounds are pro-carcinogens that …

Gut microbiota comprise microorganisms residing in the gastrointestinal tract. Some of these
microbiota are implicated in the progression of colorectal cancer (CRC). Here, we highlight …

Human cytochrome P450 1A1 (hCYP1A1) has been an object of study due to its role in
precarcinogen metabolism; for this reason it is relevant to know more in depth the …

Nitroreductases, enzymes found mostly in bacteria and also in few eukaryotes, use
nicotinamide adenine dinucleotide (NADH) or nicotinamide adenine dinucleotide phosphate …

The gut microbiota has a vast influence on human health and its role in initiating,
aggravating, or ameliorating diseases is beginning to emerge. Recently, its contribution to …

N-Nitrosodiethylamine (NDEA) is a member of nitrosamines, which is strong carcinogenic. In
order to explore an effective treatment method for NDEA removal from water, sole UV …

Gut bacterial nitroreductases play an important role in reduction of various nitroaromatic
compounds to the corresponding N-nitroso compounds, hydroxylamines or aromatic …

Background Chagas disease is a neglected illness, with limited treatments, caused by the
parasite Trypanosoma cruzi. Two drugs are prescribed to treat the disease, nifurtimox and …

Polar fractions of a sediment extract of the industrial area of Bitterfeld, Germany, have been
subjected for effect-directed identification of mutagens using the Ames fluctuation assay with …