NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca2+-
permeable component of excitatory neurotransmission in the central nervous system (CNS) …

Physical inactivity or a sedentary lifestyle is a significant health concern worldwide. The
Centers for Disease Control (CDC) recommends 150 minutes per week of moderate to …

ACTIVATION of the N-methyl-d-aspartate (NMDA) receptor is important for certain forms of
activity-dependent synaptic plasticity, such as long-term potentiation (reviewed in ref. 1), and …

The N-methyl-D-aspartate (NMDA) receptor subserves synaptic glutamate-induced
transmission and plasticity in central neurons. The yeast two-hybrid system was used to …

The hnRNPs (heterogeneous nuclear ribonucleoproteins) are RNA-binding proteins with
important roles in multiple aspects of nucleic acid metabolism, including the packaging of …

Glutamate receptors (GluRs) mediate most of the excitatory neurotransmission in the
mammalian central nervous system (CNS). In addition, they are involved in plastic changes …

Neuronal activity can lead to marked increases in the concentration of cytosolic calcium,
which then functions as a second messenger that mediates a wide range of cellular …

We have characterized the phosphorylation of the glutamate receptor subunit GluR1, using
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …

Generation, Control, and Processing of Cellular Calcium Signals Page 1 107 1040-9238/01/$.50
© 2001 by CRC Press LLC Critical Reviews in Biochemistry and Molecular Biology, 36(2):107–260 …

Abstract The PSD-95/SAP90 family of proteins has recently been implicated in the
organization of synaptic structure. Here, we describe the isolation of a novel Ras-GTPase …