Mathematical modeling of tumor-immune cell interactions
GE Mahlbacher, KC Reihmer, HB Frieboes - Journal of Theoretical Biology, 2019 - Elsevier
The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …
mounting of a prolonged and effective response to cancer growth and invasion, and for …
Multi-scale modelling and simulation in systems biology
The aim of systems biology is to describe and understand biology at a global scale where
biological functions are recognised as a result of complex mechanisms that happen at …
biological functions are recognised as a result of complex mechanisms that happen at …
Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results
P Van Liedekerke, MM Palm, N Jagiella… - Computational particle …, 2015 - Springer
In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …
Chaste: an open source C++ library for computational physiology and biology
Chaste—C ancer, H eart A nd S oft T issue E nvironment—is an open source C++ library for
the computational simulation of mathematical models developed for physiology and biology …
the computational simulation of mathematical models developed for physiology and biology …
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
The coordinated behaviour of populations of cells plays a central role in tissue growth and
renewal. Cells react to their microenvironment by modulating processes such as movement …
renewal. Cells react to their microenvironment by modulating processes such as movement …
[HTML][HTML] Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi
The functional integrity of the intestinal epithelial barrier relies on tight coordination of cell
proliferation and migration, with failure to regulate these processes resulting in disease. It is …
proliferation and migration, with failure to regulate these processes resulting in disease. It is …
Theory of hybrid dynamical systems and its applications to biological and medical systems
K Aihara, H Suzuki - … Transactions of the Royal Society A …, 2010 - royalsocietypublishing.org
In this introductory article, we survey the contents of this Theme Issue. This Theme Issue
deals with a fertile region of hybrid dynamical systems that are characterized by the …
deals with a fertile region of hybrid dynamical systems that are characterized by the …
Genetic variants in Alzheimer disease—molecular and brain network approaches
Genetic studies in late-onset Alzheimer disease (LOAD) are aimed at identifying core
disease mechanisms and providing potential biomarkers and drug candidates to improve …
disease mechanisms and providing potential biomarkers and drug candidates to improve …
Executable cancer models: successes and challenges
Making decisions on how best to treat cancer patients requires the integration of different
data sets, including genomic profiles, tumour histopathology, radiological images, proteomic …
data sets, including genomic profiles, tumour histopathology, radiological images, proteomic …
On the mathematical modeling of wound healing angiogenesis in skin as a reaction-transport process
Over the last 30 years, numerous research groups have attempted to provide mathematical
descriptions of the skin wound healing process. The development of theoretical models of …
descriptions of the skin wound healing process. The development of theoretical models of …