The understanding of the nucleotide/P2 receptor system in the regulation of renal
hemodynamics and transport function has grown exponentially over the last 20 yr. This …

Searching for stimulators of the innate antiviral response is an appealing approach to
develop novel therapeutics against viral infections. Here, we established a cell-based …

The analysis of RNA modifications is of high importance in order to address a wide range of
biological questions. Therefore, a highly sensitive and accurate method such as liquid …

In the resurging field of RNA modifications, quantification is a bottleneck blocking many
exciting avenues. With currently over 150 known nucleoside alterations, detection and …

DNA contains not only canonical nucleotides but also a variety of modifications of the bases.
In particular, cytosine and adenine are frequently modified. Determination of the exact …

Polyphosphate (polyP) kinases are widely conserved enzymes with importance in basic
bacterial metabolism and virulence in many pathogens. However, the molecular …

Chagas disease, caused by the parasitic protozoan Trypanosoma cruzi, affects over 8
million people worldwide. Current antiparasitic treatments for Chagas disease are ineffective …

The detection and quantification of methylated RNA can be beneficial to understand certain
cellular regulation processes such as transcriptional modulation of gene expression …

The interconversion of guanosine triphosphate (GTP) and guanosine diphosphate (GDP) is
known to be integral to a wide variety of biological cellular activities, yet to date there are no …

Boronate affinity adsorbents are of great promise in the enrichment of small cis-diol-
containing molecules (cis-diols) from biological matrices. This work develops a restricted …