Phototheranostics integrates deep-tissue imaging with phototherapy (containing
photothermal therapy and photodynamic therapy), holding great promise in early diagnosis …

Following the impressive progress in the treatment of relapsing–remitting multiple sclerosis
(MS), the major challenge ahead is the development of treatments to prevent or delay the …

Overactivation of microglia is associated with most neurodegenerative diseases. In this
study we examined whether PET-measurable innate immune cell activation predicts multiple …

Using a philosophical approach or deductive reasoning, we challenge the dominant clinico-
radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease …

Microglia in multiple sclerosis – pathogenesis and imaging : Current Opinion in Neurology
Microglia in multiple sclerosis – pathogenesis and imaging : Current Opinion in Neurology Log …

Background MR spectroscopic imaging (MRSI) allows in vivo assessment of brain
metabolism and is of special interest in multiple sclerosis (MS), where morphologic MRI …

Chronic active lesions are promotors of neurodegeneration and disease progression in
multiple sclerosis. They harbour a dense rim of activated innate immune cells at the lesion …

Objective To evaluate to which extent serum neurofilament light chain (NfL) increase is
related to diffusion tensor imaging–MRI measurable diffuse normal-appearing white matter …

Background Astrocytes and microglial cells are now recognized as active players in
contributing to the diffuse neuroaxonal damage associated with disease progression of …

Background and Objectives In the multiple sclerosis (MS) brain, chronic active lesions can
be detected using MRI-and PET-based methods. In this study, we investigated whether the …