Mechanistic and functional shades of mucins and associated glycans in colon cancer
Mucus serves as the chief protective barrier against pathogenic and mechanical insults in
respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major …
respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major …
Consequence of distinctive expression of MUC2 in colorectal cancers: How much is actually bad?
R Gundamaraju, WC Chong - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Colorectal cancer (CRC) exhibits complex pathogenesis via compromised intestinal
mucosal barrier. It is accepted that goblet cells secrete mucin which line the intestinal …
mucosal barrier. It is accepted that goblet cells secrete mucin which line the intestinal …
MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance
J Betge, NI Schneider, L Harbaum, MJ Pollheimer… - Virchows Archiv, 2016 - Springer
Mucin glycoprotein expression can be altered during the carcinogenic process. The impact
on the prognosis of patients with colorectal cancer (CRC) is controversial. We analyzed …
on the prognosis of patients with colorectal cancer (CRC) is controversial. We analyzed …
Mucins and associated glycan signatures in colon adenoma–carcinoma sequence: Prospective pathological implication (s) for early diagnosis of colon cancer
Abstract Development of biomarkers that detect early stage resectable premalignant lesions
of colon can provide critical aid in the prevention of colorectal cancer. Recent lines of …
of colon can provide critical aid in the prevention of colorectal cancer. Recent lines of …
[HTML][HTML] Differential expression of mucin 1 and mucin 2 in colorectal cancer
A Kasprzak, E Siodła, M Andrzejewska… - World Journal of …, 2018 - ncbi.nlm.nih.gov
AIM To determine tissue expression (mRNA, protein) of two types of mucins [mucin 1
(MUC1) and mucin 2 (MUC2)] in patients with colorectal cancer (CRC). METHODS …
(MUC1) and mucin 2 (MUC2)] in patients with colorectal cancer (CRC). METHODS …
Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling
Abstract Downregulation of Mucin 2 (MUC2) expression is associated with early
carcinogenesis events in colon cancer. MUC2 plays a role in the progression of colon …
carcinogenesis events in colon cancer. MUC2 plays a role in the progression of colon …
Role of gut microbiota and bacterial metabolites in mucins of colorectal cancer
M Gu, W Yin, J Zhang, J Yin, X Tang, J Ling… - Frontiers in Cellular …, 2023 - frontiersin.org
Colorectal cancer (CRC) is a major health burden, accounting for approximately 10% of all
new cancer cases worldwide. Accumulating evidence suggests that the crosstalk between …
new cancer cases worldwide. Accumulating evidence suggests that the crosstalk between …
Prognostic value of MUC2 expression in colorectal cancer: a systematic review and meta‐analysis
C Li, D Zuo, L Yin, Y Lin, C Li, T Liu… - … Research and Practice, 2018 - Wiley Online Library
Background. The reliability of MUC2 as a prognostic marker in colorectal cancer (CRC) is
controversial. This study evaluated the association between MUC2 expression levels in …
controversial. This study evaluated the association between MUC2 expression levels in …
Prognostic and Clinicopathological Significance of MUC Family Members in Colorectal Cancer: A Systematic Review and Meta‐Analysis
C Li, D Zuo, T Liu, L Yin, C Li… - … research and practice, 2019 - Wiley Online Library
Objective. To assess the association between MUC expression levels in colorectal cancer
(CRC) tissues and prognosis and investigate the associations between MUC expression …
(CRC) tissues and prognosis and investigate the associations between MUC expression …
Prognostic significance of MUC2, CDX2 and SOX2 in stage II colorectal cancer patients
S Ribeirinho-Soares, D Pádua, AL Amaral, E Valentini… - BMC cancer, 2021 - Springer
Background Colorectal cancer (CRC) remains a serious health concern worldwide. Despite
advances in diagnosis and treatment, about 15 to 30% of stage II CRC patients subjected to …
advances in diagnosis and treatment, about 15 to 30% of stage II CRC patients subjected to …