Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
Infection in an aging population
KA Kline, DME Bowdish - Current opinion in microbiology, 2016 - Elsevier
Highlights•One third of deaths in adults in the elderly are due to infectious disease.•Changes
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
Group B streptococcal maternal colonization and neonatal disease: molecular mechanisms and preventative approaches
Group B Streptococcus (GBS) colonizes the gastrointestinal and vaginal epithelium of a
significant percentage of healthy women, with potential for ascending intrauterine infection …
significant percentage of healthy women, with potential for ascending intrauterine infection …
Direct detection of tissue-resident bacteria and chronic inflammation in the bladder wall of postmenopausal women with recurrent urinary tract infection
NJ De Nisco, M Neugent, J Mull, L Chen… - Journal of molecular …, 2019 - Elsevier
Urinary tract infections (UTIs) are the most commonly reported infections in adult women and
have high rates of recurrence, especially in postmenopausal women. Recurrent UTI (RUTI) …
have high rates of recurrence, especially in postmenopausal women. Recurrent UTI (RUTI) …
[HTML][HTML] Roles of the vagina and the vaginal microbiota in urinary tract infection: evidence from clinical correlations and experimental models
AL Lewis, NM Gilbert - GMS infectious diseases, 2020 - ncbi.nlm.nih.gov
Mounting evidence indicates that the vagina can harbor uropathogenic bacteria. Here, we
consider three roles played by the vagina and its bacterial inhabitants in urinary tract …
consider three roles played by the vagina and its bacterial inhabitants in urinary tract …
Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease
NM Gilbert, VP O'Brien, AL Lewis - PLoS pathogens, 2017 - journals.plos.org
Pathogens often inhabit the body asymptomatically, emerging to cause disease in response
to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are …
to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are …
Polymicrobial interactions in the urinary tract: is the enemy of my enemy my friend?
JR Gaston, AO Johnson, KL Bair, AN White… - Infection and …, 2021 - Am Soc Microbiol
The vast majority of research pertaining to urinary tract infection has focused on a single
pathogen in isolation and predominantly Escherichia coli. However, polymicrobial urine …
pathogen in isolation and predominantly Escherichia coli. However, polymicrobial urine …
A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease
Recurrent bacterial infections are a significant burden worldwide, and prior history of
infection is often a significant risk factor for developing new infections. For urinary tract …
infection is often a significant risk factor for developing new infections. For urinary tract …
Strengths and limitations of model systems for the study of urinary tract infections and related pathologies
Urinary tract infections (UTIs) are some of the most common bacterial infections worldwide
and are a source of substantial morbidity among otherwise healthy women. UTIs can be …
and are a source of substantial morbidity among otherwise healthy women. UTIs can be …
An Overview of Two-Component Signal Transduction Systems Implicated in Extra-Intestinal Pathogenic E. coli Infections
EJ Breland, AR Eberly… - Frontiers in cellular and …, 2017 - frontiersin.org
Extra-intestinal pathogenic E. coli (ExPEC) infections are common in mammals and birds.
The predominant ExPEC types are avian pathogenic E. coli (APEC), neonatal meningitis …
The predominant ExPEC types are avian pathogenic E. coli (APEC), neonatal meningitis …