[HTML][HTML] A critical analysis of the CFD-DEM simulation of pharmaceutical aerosols deposition in upper intra-thoracic airways: Considerations on air flow

GH Spasov, R Rossi, A Vanossi, C Cottini… - Computers in Biology …, 2024 - Elsevier
A well-corroborated numerical methodology ensuring reproducibility in the modeling of
pharmaceutical aerosols deposition in the respiratory system via CFD-DEM simulations …

A Parametric 3D Model of Human Airways for Particle Drug Delivery and Deposition

L Geronzi, BM Fanni, B De Jong, G Roest, S Kenjeres… - Fluids, 2024 - mdpi.com
The treatment for asthma and chronic obstructive pulmonary disease relies on forced
inhalation of drug particles. Their distribution is essential for maximizing the outcomes …

Non-local impact of distal airway constrictions on patterns of inhaled particle deposition

JD Shemilt, A Horsley, JM Wild… - Royal Society …, 2024 - royalsocietypublishing.org
Airway constriction and blockage in obstructive lung diseases cause ventilation
heterogeneity and create barriers to effective drug deposition. Established computational …

Covid-19 lung infection HPC multiscale simulation based on finite element and agent-based coupled methods

A Novell Mazzara - 2024 - upcommons.upc.edu
The COVID-19 pandemic, caused by SARS-CoV-2, underscores the need for thorough
research into the virus's transmission, infection mechanisms, and treatments. This thesis …