Cannabinoid co-administration may enable reduced opioid doses for analgesia. This
updated systematic review on the opioid-sparing effects of cannabinoids considered …

Introduction: The opioid epidemic has become an immense problem in North America, and
despite decades of research on the most effective means to treat opioid use disorder (OUD) …

Background Globally, medical cannabis legalization has increased in recent years and
medical cannabis is commonly used to treat chronic pain. However, there are few …

Objective To assess the efficacy and harms of adding medical cannabis to prescription
opioids among people living with chronic pain. Design Systematic review. Data sources …

The National Academies of Sciences, Engineering, and Medicine has found substantial
evidence that cannabis (plant) is effective for the treatment of chronic pain in adults, and …

Chronic pain is common, costly, and challenging to treat. Many individuals with chronic pain
have turned to cannabis as an alternative form of pain management. We report results from …

Background Understanding the association of polydrug use disorders (PUD) with
psychosocial and clinical factors is essential for the treatment of individuals with opioid use …

Aims Preclinical studies demonstrate that cannabidiol (CBD) elicits an antinociceptive
response in animal models of neuropathic pain; in humans, limited data are available to …

Oxycodone, a semisynthetic derivative of naturally occurring thebaine, an opioid alkaloid,
has been available for more than 100 years. Although thebaine cannot be used …

The side effects of cancer therapy continue to cause significant health and cost burden to the
patient, their friends and family, and governments. A major barrier in the way in which these …