[HTML][HTML] Role of phospholipases A2 in vascular relaxation and sympatholytic effects of five Australian Brown Snake, Pseudonaja spp., venoms in rat isolated tissues

NT Vuong, TNW Jackson, CE Wright - Frontiers in Pharmacology, 2021 - frontiersin.org
Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially
life-threatening hypotension and subsequent cardiovascular collapse. There have been …

Endothelin B receptor dysfunction mediates elevated myogenic tone in cerebral arteries from aged male Fischer 344 rats

AP Young, J Zhu, AM Bagher, EM Denovan-Wright… - Geroscience, 2021 - Springer
The human brain requires adequate cerebral blood flow to meet the high demand for
nutrients and to clear waste products. With age, there is a chronic reduction in cerebral …

[PDF][PDF] Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men.

K Tagawa, SG Ra, H Kumagai, T Yoshikawa… - Physiological …, 2018 - biomed.cas.cz
Arterial compliance (AC) is an index of the elasticity of large arteries. Endothelial dysfunction
has been reported to result in reduced arterial compliance, which represents increased …

Cannabidiol selectively inhibits the contraction of rat small resistance arteries: Possible role for CGRP and voltage-gated calcium channels

AC Mazeh, JA Angus, CE Wright - European Journal of Pharmacology, 2021 - Elsevier
The pharmacology of cannabidiol, the non-psychoactive major component of Cannabis
sativa, is of growing interest as it becomes more widely prescribed. This study aimed to …

Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients

G Ozen, C Benyahia, Y Amgoud, J Patel… - Prostaglandins & Other …, 2020 - Elsevier
Pulmonary hypertension (PH) is characterized by an elevation of mean pulmonary artery
pressure and it is classified into five groups. Among these groups, PH Group-III is defined as …

Direkte pharmakologische Gq-Protein-Modulation in pulmonalen Gefäßen

A Seidinger - 2023 - bonndoc.ulb.uni-bonn.de
Heterotrimere G-Proteine können in vier Familien entsprechend ihrer alpha-Untereinheit
unterteilt werden (Gs, Gi, G12/13 und Gq). Sie überführen ein extrazelluläres Signal nach …

[PDF][PDF] Role of Phospholipases A2 in Vascular Relaxation and Sympatholytic Effects of Five Australian Brown Snake

NT Vuong, TNW Jackson, CE Wright - 2021 - academia.edu
Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially
life-threatening hypotension and subsequent cardiovascular collapse. There have been …

Role of endothelin-1 clearance in the haemodynamic responses to endothelin-1 in the pulmonary and hindquarter vasculature of anaesthetised rats.

JA Angus, CE Wright - European Journal of Pharmacology, 2019 - Elsevier
In the pulmonary vasculature there is clearance of endothelin-1 from the circulation
mediated by endothelin ET B receptors. This study explored the haemodynamic effects of …