Rifamycins are a class of antibiotics that were first discovered in 1957 and are known for
their use in treating tuberculosis (TB). Rifamycins exhibit bactericidal activity against many …

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. Despite decades of research driving advancements in drug development and …

Bacterial resistance remains a significant threat and a leading cause of death worldwide,
despite massive attempts to control infections. In an effort to develop biologically active …

Low-level rifampin resistance associated with specific rpoB mutations (referred as
“disputed”) in Mycobacterium tuberculosis is easily missed by some phenotypic methods. To …

Carbon dots have many new and interesting phenomena, and the concentration dependent
luminescence wavelength is an intriguing one. Herein, nitrogen-sulfur co-doped carbon dots …

The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB),
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …

Pyrazinamide is an essential first‐line antitubercular drug which plays pivotal role in
tuberculosis treatment. It is a prodrug that requires amide hydrolysis by mycobacterial …

The discovery of molecules that could shorten the treatment period of tuberculosis (TB)
holds the promise of improving the current regimen. Polyamines are organic polycationic …

Emerging Mycobacterium tuberculosis (Mtb) resistant strains have continued to limit the
efficacies of existing antitubercular therapies. More specifically, mutations in the RNA …

Curcumin is an important bioactive component of turmeric and also one of the important
natural products, which has been investigated extensively. The precise mode of action of …