Targeting the folate receptor: improving efficacy in inorganic medicinal chemistry

PM Carron, A Crowley, D O'Shea… - Current Medicinal …, 2018 - ingentaconnect.com
The discovery of the high-affinity, high-specificity folate receptor in mamalian kidney cells,
coupled with the ability of folate to enter cells by folate receptor-mediated endocytosis and …

A luminescent amine-functionalized metal–organic framework conjugated with folic acid as a targeted biocompatible pH-responsive nanocarrier for apoptosis …

R Abazari, F Ataei, A Morsali, AMZ Slawin… - … applied materials & …, 2019 - ACS Publications
Folic acid amine-functionalized metal–organic framework (FOLA@ NH2-Eu: TMU-62) with
luminescent properties loaded with 5-fluorouracil (5-Fu), as an anticancer medication, was …

Folic acid and sodium folate salts: Thermal behavior and spectroscopic (IR, Raman, and solid-state 13C NMR) characterization

VR Magri, MA Rocha, CS de Matos… - … Acta Part A: Molecular …, 2022 - Elsevier
Folic acid (FA; vitamin B9) and its associated sodium salts, strongly relevant for many
scientific and technological applications-from nutrition to pharmacology and nanomedicine …

Synthesis, spectroscopic characterization, molecular docking, and evaluation of antibacterial potential of transition metal complexes obtained using triazole chelating …

NS Al-Radadi, EM Zayed, GG Mohamed… - Journal of …, 2020 - Wiley Online Library
Mononuclear chelates of Ni (II), Co (II), Fe (III), Cd (II), and Cu (II) derived from triazole novel
tridentate ligands were prepared and characterized by different spectroscopic methods. The …

The synthesis and characterisation of strontium and calcium folates with potential osteogenic activity

L Rojo, S Radley-Searle… - Journal of Materials …, 2015 - pubs.rsc.org
Compounds having the general formula MFO· 4H2O where M= Ca or Sr and FO= a folate
anion were prepared and their structure and physico-chemical properties were determined …

Novel Triazole Thiole ligand and some of its metal chelates: Synthesis, structure charactertization, thermal behavior in comparison withcomputational caculations …

EM Zayed, MA Zayed, HA Abd El Salam… - … biology and chemistry, 2019 - Elsevier
Structural and molecular properties of HL, 4-amino-5-(2, 2-dichloro-1-methylcyclopropyl)-4H-
1, 2, 4-triazole-3-thiol toward the transition metal ions namely Fe (III), Co (II) and Ni (II) had …

Pyrolysis of folic acid: Identification of gaseous/volatile products and structural evolution of N-doped graphitic carbon

VR Magri, CS de Matos, MA Rocha, C Taviot-Gueho… - Thermochimica …, 2024 - Elsevier
Folic acid (FA) is a low-cost and suitable source for producing different N-doped carbon
materials by pyrolysis. However, the pyrolytic steps of FA are not entirely understood …

Vitamin B9 derivatives as carriers of bioactive cations for musculoskeletal regeneration applications: Synthesis, characterization and biological evaluation

D Fernández-Villa, G Asensio, M Silva… - European Journal of …, 2021 - Elsevier
a bstract The development of new drugs for musculoskeletal regeneration purposes has
attracted much attention in the last decades. In this work, we present three novel vitamin B9 …

Thermal behaviour of some biologically active species based on complexes with a triazolopyrimidine pharmacophore

R Olar, L Calu, M Badea, MC Chifiriuc, C Bleotu… - Journal of Thermal …, 2017 - Springer
A series of complexes of type M (pmtp)(CH 3 COO) 2· nH 2 O ((1) M: Co, n= 4.5;(2) M: Ni, n=
3.5;(3) M: Cu, n= 0.5;(4) M: Zn, n= 0; pmtp: 5-phenyl-7-methyl-1, 2, 4-triazolo [1, 5-a] …

Synthesis, structural characterization, thermal behaviour and antimicrobial activity of copper, cadmium and zinc chelates of traizole-thiole ligand in comparison with …

H Abdelsalaam, EM Zayed… - Egyptian Journal of …, 2019 - ejchem.journals.ekb.eg
This research involved structural and molecular behaviour of the ligand HL, 4-amino-5-(2, 2-
dichloro-1-methylcyclopropyl)-4H-1, 2, 4-triazole-3-thiol toward the transition metal ions …